소비자제품 중 구아니딘계 올리고머의 정량을 위한 Eosin Y를 이용한 흡광분석법의 최적화

Abstract

A spectroscopic method using a specific interaction between guanidine groups and 2,4,5,7- tetrabromo-6- oxido- 3-oxo-3H-xanthen-9-yl)benzoate (Eosin Y) for quantifying guanidine oligomers from consumer products was optimized. Specifically, reaction time, detection wavelength, pH condition, and solid-phase extraction were optimized with the method detection limits of 0.133, 0.155, and 0.195 mg/L for polyhexamethylene guanidine (PHMG), polyhexamethylene biguanidine (PHMB), poly(2-(2-ethoxy)ethoxyethyl guanidium hydrochloride (PGH), respectively. Using the method, the content of guanidine oligomers were determined from various consumer products (wet tissues, contact lens cleaners, and make-up removers). This method can be used for detecting the existence of guanidine oligomers from consumer products as a screening tool.