Evaluation of the cytotoxicity of gold nanoparticle-quercetin complex and its potential as a drug delivery vesicle
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Pak, P.J. | - |
dc.contributor.author | Go, E.B. | - |
dc.contributor.author | Hwang, M.H. | - |
dc.contributor.author | Lee, D.G. | - |
dc.contributor.author | Cho, M.J. | - |
dc.contributor.author | Joo, Y.H. | - |
dc.contributor.author | Chung, N. | - |
dc.date.accessioned | 2021-09-04T08:55:34Z | - |
dc.date.available | 2021-09-04T08:55:34Z | - |
dc.date.created | 2021-06-17 | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 1976-0442 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/91422 | - |
dc.description.abstract | Recently, conjugates of medicinal herb-derived bioflavonoids, such as quercetin, and gold nanoparticles (GNPs) have gained attention as targeted drug delivery systems. In the present study, because quercetin is an important flavonoid with anticancer, anti-inflammatory, and anti-oxidant properties, GNP-quercetin complexes (GNPQs) were synthesized to investigate possible adverse effects such as cytotoxicity. We found that while quercetin was cytotoxic, GNPQs were not cytotoxic towards the RAW 264.7 and THP-1 cell lines. Therefore, GNPQs may serve as a potential drug delivery system for cancer treatment. © The Korean Society for Applied Biological Chemistry 2016. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | Korean Society for Applied Biological Chemistry | - |
dc.title | Evaluation of the cytotoxicity of gold nanoparticle-quercetin complex and its potential as a drug delivery vesicle | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Chung, N. | - |
dc.identifier.doi | 10.3839/jabc.2016.026 | - |
dc.identifier.scopusid | 2-s2.0-84976484682 | - |
dc.identifier.bibliographicCitation | Journal of Applied Biological Chemistry, v.59, no.2, pp.145 - 147 | - |
dc.relation.isPartOf | Journal of Applied Biological Chemistry | - |
dc.citation.title | Journal of Applied Biological Chemistry | - |
dc.citation.volume | 59 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 145 | - |
dc.citation.endPage | 147 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002116052 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordAuthor | Citrate synthesis | - |
dc.subject.keywordAuthor | Drug delivery system | - |
dc.subject.keywordAuthor | Gold nanoparticle | - |
dc.subject.keywordAuthor | Quercetin | - |
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