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Evaluation of the cytotoxicity of gold nanoparticle-quercetin complex and its potential as a drug delivery vesicle

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dc.contributor.authorPak, P.J.-
dc.contributor.authorGo, E.B.-
dc.contributor.authorHwang, M.H.-
dc.contributor.authorLee, D.G.-
dc.contributor.authorCho, M.J.-
dc.contributor.authorJoo, Y.H.-
dc.contributor.authorChung, N.-
dc.date.accessioned2021-09-04T08:55:34Z-
dc.date.available2021-09-04T08:55:34Z-
dc.date.created2021-06-17-
dc.date.issued2016-
dc.identifier.issn1976-0442-
dc.identifier.urihttps://scholar.korea.ac.kr/handle/2021.sw.korea/91422-
dc.description.abstractRecently, conjugates of medicinal herb-derived bioflavonoids, such as quercetin, and gold nanoparticles (GNPs) have gained attention as targeted drug delivery systems. In the present study, because quercetin is an important flavonoid with anticancer, anti-inflammatory, and anti-oxidant properties, GNP-quercetin complexes (GNPQs) were synthesized to investigate possible adverse effects such as cytotoxicity. We found that while quercetin was cytotoxic, GNPQs were not cytotoxic towards the RAW 264.7 and THP-1 cell lines. Therefore, GNPQs may serve as a potential drug delivery system for cancer treatment. © The Korean Society for Applied Biological Chemistry 2016.-
dc.languageEnglish-
dc.language.isoen-
dc.publisherKorean Society for Applied Biological Chemistry-
dc.titleEvaluation of the cytotoxicity of gold nanoparticle-quercetin complex and its potential as a drug delivery vesicle-
dc.typeArticle-
dc.contributor.affiliatedAuthorChung, N.-
dc.identifier.doi10.3839/jabc.2016.026-
dc.identifier.scopusid2-s2.0-84976484682-
dc.identifier.bibliographicCitationJournal of Applied Biological Chemistry, v.59, no.2, pp.145 - 147-
dc.relation.isPartOfJournal of Applied Biological Chemistry-
dc.citation.titleJournal of Applied Biological Chemistry-
dc.citation.volume59-
dc.citation.number2-
dc.citation.startPage145-
dc.citation.endPage147-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.identifier.kciidART002116052-
dc.description.journalClass1-
dc.description.journalRegisteredClassscopus-
dc.description.journalRegisteredClasskci-
dc.subject.keywordAuthorCitrate synthesis-
dc.subject.keywordAuthorDrug delivery system-
dc.subject.keywordAuthorGold nanoparticle-
dc.subject.keywordAuthorQuercetin-
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