MATHEMATICAL MODEL AND ITS FAST NUMERICAL METHOD FOR THE TUMOR GROWTH

Abstract

In this paper, we reformulate the diffuse interface model of the tumor growth (S.M. Wise et al., Three-dimensional multispecies nonlinear tumor growth-I: model and numerical method, J. Theor. Biol. 253 (2008) 524-543). In the new proposed model, we use the conservative second-order Allen-Cahn equation with a space-time dependent Lagrange multiplier instead of using the fourth-order Cahn-Hilliard equation in the original model. To numerically solve the new model, we apply a recently developed hybrid numerical method. We perform various numerical experiments. The computational results demonstrate that the new model is not only fast but also has a good feature such as distributing excess mass from the inside of tumor to its boundary regions.