A Simple Geometric Assessment of Perfusion Lesion Volume at Hyperacute Stage of Ischemic Stroke in Patients with Symptomatic Steno-Occlusion of Major Cerebral Arteries and Risk of Subsequent Cerebral Ischemic Events
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kang, Jihoon | - |
dc.contributor.author | Jung, Cheolkyu | - |
dc.contributor.author | Kim, Nayoung | - |
dc.contributor.author | Son, Yoo Ri | - |
dc.contributor.author | Choi, Byungse | - |
dc.contributor.author | Kim, Jae-Hyoung | - |
dc.contributor.author | Lee, Ji Sung | - |
dc.contributor.author | Lee, Juneyoung | - |
dc.contributor.author | Lee, Jun | - |
dc.contributor.author | Jang, Myung Suk | - |
dc.contributor.author | Yang, Mi Hwa | - |
dc.contributor.author | Han, Moon-Ku | - |
dc.contributor.author | Bae, Hee-Joon | - |
dc.date.accessioned | 2021-09-04T09:58:39Z | - |
dc.date.available | 2021-09-04T09:58:39Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2015-12 | - |
dc.identifier.issn | 1052-3057 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/91694 | - |
dc.description.abstract | Our objective is to elucidate the association of baseline perfusion lesion volume on perfusion-weighted magnetic resonance imaging (PWI) obtained at hyperacute stage of ischemic stroke with subsequent cerebral ischemic events (SIEs) in patients with symptomatic steno-occlusion of major cerebral arteries. Using a prospective stroke registry database, patients arriving within 24 hours of onset with symptomatic steno-occlusion of major supratentorial cerebral arteries were identified. On baseline PWI, time-to-peak lesion volume (TTP-LV) was determined by a simple geometric method and dichotomized into the highest tertile (large) and the other tertiles (small to medium) according to the vascular territory of occluded arteries. Primary outcome was a time to SIE up to 1 year after stroke onset. A total of 385 patients (a median time delay from onset to arrival, 2.2 hours) were enrolled. During the first year of stroke, the SIE rate of the large TTP-LV group was twice that of the small-to-medium TTP-LV group (35.7% versus 17.4%; P < .001). Large TTP-LV independently raised the hazard of SIE (hazard ratio, 2.24; 95% confidence interval, 1.45-3.44). This study demonstrates that TTP-LV on PWI measured through a simple geometric method at an emergency setting can be used to predict progression or recurrence of ischemic stroke in patients with symptomatic steno-occlusion of major cerebral arteries. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER | - |
dc.subject | EARLY NEUROLOGICAL DETERIORATION | - |
dc.subject | RECURRENT STROKE | - |
dc.subject | PREVENTION | - |
dc.subject | PREDICTION | - |
dc.subject | SELECTION | - |
dc.subject | OUTCOMES | - |
dc.title | A Simple Geometric Assessment of Perfusion Lesion Volume at Hyperacute Stage of Ischemic Stroke in Patients with Symptomatic Steno-Occlusion of Major Cerebral Arteries and Risk of Subsequent Cerebral Ischemic Events | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Juneyoung | - |
dc.identifier.doi | 10.1016/j.jstrokecerebrovasdis.2015.05.025 | - |
dc.identifier.scopusid | 2-s2.0-84949663934 | - |
dc.identifier.wosid | 000367388800005 | - |
dc.identifier.bibliographicCitation | JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, v.24, no.12, pp.2669 - 2675 | - |
dc.relation.isPartOf | JOURNAL OF STROKE & CEREBROVASCULAR DISEASES | - |
dc.citation.title | JOURNAL OF STROKE & CEREBROVASCULAR DISEASES | - |
dc.citation.volume | 24 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 2669 | - |
dc.citation.endPage | 2675 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.relation.journalWebOfScienceCategory | Peripheral Vascular Disease | - |
dc.subject.keywordPlus | EARLY NEUROLOGICAL DETERIORATION | - |
dc.subject.keywordPlus | RECURRENT STROKE | - |
dc.subject.keywordPlus | PREVENTION | - |
dc.subject.keywordPlus | PREDICTION | - |
dc.subject.keywordPlus | SELECTION | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.subject.keywordAuthor | Cerebral ischemia | - |
dc.subject.keywordAuthor | perfusion | - |
dc.subject.keywordAuthor | recurrence | - |
dc.subject.keywordAuthor | progression | - |
dc.subject.keywordAuthor | stenosis and cerebrovascular occlusion | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
145 Anam-ro, Seongbuk-gu, Seoul, 02841, Korea+82-2-3290-2963
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.