The use of fluorine-18 fluorodeoxyglucose positron emission tomography for imaging human motor neuronal activation in the brain
- Authors
- Pahk, Kisoo; Park, Kun-Woo; Pyun, Sung Bom; Lee, Jae Sung; Kim, Sungeun; Choe, Jae Gol
- Issue Date
- 12월-2015
- Publisher
- SPANDIDOS PUBL LTD
- Keywords
- motor cortex; motor cortex activation; motor image; neuroimaging; fluorodeoxyglucose positron emission tomography
- Citation
- EXPERIMENTAL AND THERAPEUTIC MEDICINE, v.10, no.6, pp.2126 - 2130
- Indexed
- SCIE
SCOPUS
- Journal Title
- EXPERIMENTAL AND THERAPEUTIC MEDICINE
- Volume
- 10
- Number
- 6
- Start Page
- 2126
- End Page
- 2130
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/91712
- DOI
- 10.3892/etm.2015.2788
- ISSN
- 1792-0981
- Abstract
- The present study aimed to visualize human motor neuronal activation in the brain using fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET), and to develop an FDG-PET procedure for imaging neuronal activation. A male volunteer underwent 20 min periods of rest and motor activation, whilst being assessed using FDG-PET on two consecutive days. The motor task, which involved repetitively grasping and releasing the right hand, was performed during the initial 5 min of the activation period. Subtraction of the rest period signal from the activation PET images was performed using the subtraction ictal single-photon emission computed tomography co-registered to magnetic resonance imaging method. The subtracted image detected activation of the contralateral (left) primary motor cortex, supplementary motor area, and ipsilateral (right) cerebellum. In the present study, FDG-PET detected significantly increased motor-associated activation of the brain in a subject performing a motor task.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
- Graduate School > Department of Biomedical Sciences > 1. Journal Articles
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