Chronic kidney disease and intravenous thrombolysis in acute stroke: A systematic review and meta-analysis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jung, Jin-Man | - |
dc.contributor.author | Kim, Hyun Jung | - |
dc.contributor.author | Ahn, Hyeongsik | - |
dc.contributor.author | Ahn, Il Min | - |
dc.contributor.author | Do, Youngrok | - |
dc.contributor.author | Choi, Jeong-Yoon | - |
dc.contributor.author | Seo, Woo-Keun | - |
dc.contributor.author | Oh, Kyungmi | - |
dc.contributor.author | Cho, Kyung-Hee | - |
dc.contributor.author | Yu, Sungwook | - |
dc.date.accessioned | 2021-09-04T10:33:51Z | - |
dc.date.available | 2021-09-04T10:33:51Z | - |
dc.date.created | 2021-06-10 | - |
dc.date.issued | 2015-11-15 | - |
dc.identifier.issn | 0022-510X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/91895 | - |
dc.description.abstract | Background: The association between chronic kidney disease (CKD) and hemorrhagic complications or clinical outcomes in patients treated with intravenous (IV) thrombolytic agents is controversial. Methods: We searched multiple databases for studies on the association between CKD and symptomatic intracerebral hemorrhage (ICH) and/or clinical outcomes in acute stroke patients treated with IV tissue plasminogen activator (tPA). Observational studies that evaluated the association between CKD and outcomes after adjusting for other confounding factors were eligible. We assessed study quality and performed a meta-analysis. The main outcome was symptomatic ICH. The secondary outcomes were poor functional status at 3 months using the modified Rankin Scale, mortality at 3 months, and any ICH. Results: Seven studies were selected based on our eligibility criteria. Of 7168 patients treated with IV tPA, 2001 (27.9%) had CKD. Patients with CKD had a higher risk of symptomatic ICH and mortality [pooled odds ratio (OR) 1.56, 95% confidence interval (Cl) 1.05-233 and pooled OR 1.70,95% CI 1.03-2.81, respectively]. Patients with CKD were likely to have an increased risk of poor outcome at 3 months. There was no significant association between CKD and any ICH. Conclusions: Chronic kidney disease may significantly affect symptomatic hemorrhagic complications and poor clinical outcomes following administration of IV tPA. (C) 2015 Elsevier B.V. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER | - |
dc.subject | SYMPTOMATIC INTRACEREBRAL HEMORRHAGE | - |
dc.subject | TISSUE-PLASMINOGEN ACTIVATOR | - |
dc.subject | RENAL DYSFUNCTION | - |
dc.subject | ISCHEMIC-STROKE | - |
dc.subject | RISK-FACTOR | - |
dc.subject | RT-PA | - |
dc.subject | THERAPY | - |
dc.subject | OUTCOMES | - |
dc.subject | IMPAIRMENT | - |
dc.subject | ALTEPLASE | - |
dc.title | Chronic kidney disease and intravenous thrombolysis in acute stroke: A systematic review and meta-analysis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jung, Jin-Man | - |
dc.contributor.affiliatedAuthor | Kim, Hyun Jung | - |
dc.contributor.affiliatedAuthor | Ahn, Hyeongsik | - |
dc.contributor.affiliatedAuthor | Seo, Woo-Keun | - |
dc.contributor.affiliatedAuthor | Oh, Kyungmi | - |
dc.contributor.affiliatedAuthor | Cho, Kyung-Hee | - |
dc.contributor.affiliatedAuthor | Yu, Sungwook | - |
dc.identifier.doi | 10.1016/j.jns.2015.09.353 | - |
dc.identifier.scopusid | 2-s2.0-84956586011 | - |
dc.identifier.wosid | 000365050200056 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THE NEUROLOGICAL SCIENCES, v.358, no.1-2, pp.345 - 350 | - |
dc.relation.isPartOf | JOURNAL OF THE NEUROLOGICAL SCIENCES | - |
dc.citation.title | JOURNAL OF THE NEUROLOGICAL SCIENCES | - |
dc.citation.volume | 358 | - |
dc.citation.number | 1-2 | - |
dc.citation.startPage | 345 | - |
dc.citation.endPage | 350 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.subject.keywordPlus | SYMPTOMATIC INTRACEREBRAL HEMORRHAGE | - |
dc.subject.keywordPlus | TISSUE-PLASMINOGEN ACTIVATOR | - |
dc.subject.keywordPlus | RENAL DYSFUNCTION | - |
dc.subject.keywordPlus | ISCHEMIC-STROKE | - |
dc.subject.keywordPlus | RISK-FACTOR | - |
dc.subject.keywordPlus | RT-PA | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.subject.keywordPlus | IMPAIRMENT | - |
dc.subject.keywordPlus | ALTEPLASE | - |
dc.subject.keywordAuthor | Chronic kidney disease | - |
dc.subject.keywordAuthor | Meta-analysis | - |
dc.subject.keywordAuthor | Stroke | - |
dc.subject.keywordAuthor | Outcome | - |
dc.subject.keywordAuthor | Systematic review | - |
dc.subject.keywordAuthor | Tissue-type plasminogen activator | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.