A Double-Chambered Protein Nanocage Loaded with Thrombin Receptor Agonist Peptide (TRAP) and gamma-Carboxyglutamic Acid of Protein C (PC-Gla) for Sepsis Treatment
DC Field | Value | Language |
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dc.contributor.author | Lee, Wonhwa | - |
dc.contributor.author | Seo, Junyoung | - |
dc.contributor.author | Kwak, Soyoung | - |
dc.contributor.author | Park, Eun Ji | - |
dc.contributor.author | Na, Dong Hee | - |
dc.contributor.author | Kim, Soyoun | - |
dc.contributor.author | Lee, You Mie | - |
dc.contributor.author | Kim, In-San | - |
dc.contributor.author | Bae, Jong-Sup | - |
dc.date.accessioned | 2021-09-04T10:44:54Z | - |
dc.date.available | 2021-09-04T10:44:54Z | - |
dc.date.created | 2021-06-10 | - |
dc.date.issued | 2015-11-11 | - |
dc.identifier.issn | 0935-9648 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/91917 | - |
dc.description.abstract | New protein nanocages are designed bearing two functional proteins, gamma-carboxyglutamic acid of protein C (PC-Gla) and thrombin receptor agonist peptide (TRAP), and have an anti-septic response. These nanoparticles reduce sepsis-induced organ injury and septic mortality in vivo. Noting that there are currently no medications for severe sepsis, these results show that novel nanoparticles can be used to treat sepsis. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.subject | ENDOTHELIAL-CELLS | - |
dc.subject | ADHESION MOLECULES | - |
dc.subject | SERUM FERRITIN | - |
dc.subject | NANOPARTICLES | - |
dc.subject | ACTIVATION | - |
dc.subject | EXPRESSION | - |
dc.subject | PATHWAY | - |
dc.subject | ANTICOAGULANT | - |
dc.subject | EPIDEMIOLOGY | - |
dc.subject | PERMEABILITY | - |
dc.title | A Double-Chambered Protein Nanocage Loaded with Thrombin Receptor Agonist Peptide (TRAP) and gamma-Carboxyglutamic Acid of Protein C (PC-Gla) for Sepsis Treatment | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, In-San | - |
dc.identifier.doi | 10.1002/adma.201503093 | - |
dc.identifier.scopusid | 2-s2.0-84946763409 | - |
dc.identifier.wosid | 000364700200011 | - |
dc.identifier.bibliographicCitation | ADVANCED MATERIALS, v.27, no.42, pp.6637 - + | - |
dc.relation.isPartOf | ADVANCED MATERIALS | - |
dc.citation.title | ADVANCED MATERIALS | - |
dc.citation.volume | 27 | - |
dc.citation.number | 42 | - |
dc.citation.startPage | 6637 | - |
dc.citation.endPage | + | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Physical | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.relation.journalWebOfScienceCategory | Physics, Condensed Matter | - |
dc.subject.keywordPlus | ENDOTHELIAL-CELLS | - |
dc.subject.keywordPlus | ADHESION MOLECULES | - |
dc.subject.keywordPlus | SERUM FERRITIN | - |
dc.subject.keywordPlus | NANOPARTICLES | - |
dc.subject.keywordPlus | ACTIVATION | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | PATHWAY | - |
dc.subject.keywordPlus | ANTICOAGULANT | - |
dc.subject.keywordPlus | EPIDEMIOLOGY | - |
dc.subject.keywordPlus | PERMEABILITY | - |
dc.subject.keywordAuthor | ferritin | - |
dc.subject.keywordAuthor | nanoparticles | - |
dc.subject.keywordAuthor | PC-gla | - |
dc.subject.keywordAuthor | sepsis | - |
dc.subject.keywordAuthor | TRAP | - |
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