Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Exaggerated Exercise Blood Pressure Response During Treadmill Testing as a Predictor of Future Hypertension in Men: A Longitudinal Study

Authors
Jae, Sae YoungFranklin, Barry A.Choo, JinaChoi, Yoon-HoFernhall, Bo
Issue Date
11월-2015
Publisher
OXFORD UNIV PRESS
Keywords
blood pressure; cutoff values; exercise blood pressure; hypertension; incident hypertension
Citation
AMERICAN JOURNAL OF HYPERTENSION, v.28, no.11, pp.1362 - 1367
Indexed
SCIE
SCOPUS
Journal Title
AMERICAN JOURNAL OF HYPERTENSION
Volume
28
Number
11
Start Page
1362
End Page
1367
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/92088
DOI
10.1093/ajh/hpv036
ISSN
0895-7061
Abstract
BACKGROUND The purpose of this study was to evaluate receiver operating characteristic curves to identify optimal cutoff values of exercise systolic blood pressure (SBP) using both peak SBP and relative SBP (peak SBP minus resting SBP) as predictors of future hypertension (HTN). METHODS Participants were 3,742 healthy normotensive men who underwent symptom-limited treadmill testing at baseline. Incident HTN was defined as SBP/diastolic blood pressure greater than 140/90 mm Hg and/or diagnosed HTN by a physician. RESULTS During an average 5-year follow-up, 364 (9.7%) new cases of HTN were observed. The most discriminatory cutoff values for peak SBP and relative SBP for predicting incident HTN were 181 mm Hg (areas under the curve (AUC) = 0.644, sensitivity = 54%, and specificity = 69%) and 52 mm Hg (AUC = 0.549, sensitivity = 64.3%, and specificity = 44.6%), respectively. Participants with peak SBP greater than 181 mm Hg and relative SBP greater than 52 mm Hg had 1.54-fold (95% CI: 1.23-1.93) and 1.44-fold (95% CI: 1.16-1.80) risks of developing HTN after adjusting for potential confounding variables. When these 2 variables were entered simultaneously into the Cox proportional hazards regression model with adjustment for potential confounding variables, only peak SBP (relative risk: 1.39, 95% CI: 1.02-1.89) was a predictor of the development of HTN. CONCLUSIONS The most accurate discriminators for peak and relative SBP during treadmill exercise testing to predict incident HTN were greater than 181 and 52 mm Hg, respectively, in normotensive men. A peak SBP greater than 181 mm Hg during treadmill exercise testing may provide a useful predictor for the development of HTN in clinical practice.
Files in This Item
There are no files associated with this item.
Appears in
Collections
College of Nursing > Department of Nursing > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Choo, Jin a photo

Choo, Jin a
간호대학 (간호학과)
Read more

Altmetrics

Total Views & Downloads

BROWSE