Unusual severe cases of type 1 porcine reproductive and respiratory syndrome virus (PRRSV) infection in conventionally reared pigs in South Korea
DC Field | Value | Language |
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dc.contributor.author | Lyoo, Kwang-Soo | - |
dc.contributor.author | Yeom, Minjoo | - |
dc.contributor.author | Choi, Jong-Young | - |
dc.contributor.author | Park, Jong-Hwan | - |
dc.contributor.author | Yoon, Sun-Woo | - |
dc.contributor.author | Song, Daesub | - |
dc.date.accessioned | 2021-09-04T11:19:39Z | - |
dc.date.available | 2021-09-04T11:19:39Z | - |
dc.date.created | 2021-06-10 | - |
dc.date.issued | 2015-10-24 | - |
dc.identifier.issn | 1746-6148 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/92163 | - |
dc.description.abstract | Background: Porcine reproductive and respiratory syndrome virus (PRRSV) causes a loss of approximately US$ 70 million every year to the South Korean pork industry. There are two distinct genotypes: European (type 1) and North American (type 2). In South Korea, type 1 and type 2 PRRSV are widely distributed and have evolved continuously since the infection was first described. Here, we present two field cases of type 1 PRRSV infection with unusually severe pathogenicity. Case presentation: The first case farm was a two-site production system comprising farrow-to-grower and grower-to-finish units and was historically free from PRRSV infections. The PRRSV vaccine had not been used in both units. In October 2014, pigs in the grower-to-finish unit experienced severe respiratory distress with the mortality rate reaching to 22 %. Despite antibiotic treatment, clinical signs were still noticed in most pigs. The second case farm was also a two-site production system, but had two separate farrow-to-grower units (unit A and unit B). Historically, type 1 PRRSV was continuously present in unit A, but unit B was free from PRRSV. Thus, all grower pigs of unit B were vaccinated before being moved to the grower-to-finish unit. In November 2014, severe respiratory distress was seen in pigs of the grower-to-finish unit. Significant respiratory distress was observed in only the grower herd moved from unit B, and the mortality of those pigs was similar to 50 %. However, no disease was shown in the grower pigs from unit A. Conclusions: To our knowledge, the present study is the first observation of the cases of infection by highly pathogenic type 1 PRRSV in South Korea. The Korean type 1 PRRSV strains have undergone unique evolutionary dynamics for the last decade in this country. Although there are known to be three clusters of Korean type 1 PRRSV, their pathogenicity could not be categorized owing to their high level of genetic diversity. Therefore, further studies are needed to demonstrate the novel classification of Korean type 1 PRRSV strains according to their virulence factors. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | BMC | - |
dc.subject | NORTH-AMERICAN | - |
dc.subject | PATHOGENICITY | - |
dc.subject | EVOLUTIONARY | - |
dc.subject | PATHOGENESIS | - |
dc.subject | CHALLENGE | - |
dc.subject | RESPONSES | - |
dc.subject | GENOTYPES | - |
dc.subject | EFFICACY | - |
dc.subject | VACCINE | - |
dc.subject | STRAIN | - |
dc.title | Unusual severe cases of type 1 porcine reproductive and respiratory syndrome virus (PRRSV) infection in conventionally reared pigs in South Korea | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Song, Daesub | - |
dc.identifier.doi | 10.1186/s12917-015-0584-5 | - |
dc.identifier.scopusid | 2-s2.0-84944704350 | - |
dc.identifier.wosid | 000363443300003 | - |
dc.identifier.bibliographicCitation | BMC VETERINARY RESEARCH, v.11 | - |
dc.relation.isPartOf | BMC VETERINARY RESEARCH | - |
dc.citation.title | BMC VETERINARY RESEARCH | - |
dc.citation.volume | 11 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Veterinary Sciences | - |
dc.relation.journalWebOfScienceCategory | Veterinary Sciences | - |
dc.subject.keywordPlus | NORTH-AMERICAN | - |
dc.subject.keywordPlus | PATHOGENICITY | - |
dc.subject.keywordPlus | EVOLUTIONARY | - |
dc.subject.keywordPlus | PATHOGENESIS | - |
dc.subject.keywordPlus | CHALLENGE | - |
dc.subject.keywordPlus | RESPONSES | - |
dc.subject.keywordPlus | GENOTYPES | - |
dc.subject.keywordPlus | EFFICACY | - |
dc.subject.keywordPlus | VACCINE | - |
dc.subject.keywordPlus | STRAIN | - |
dc.subject.keywordAuthor | Type 1 PRRSV | - |
dc.subject.keywordAuthor | South Korea | - |
dc.subject.keywordAuthor | Highly pathogenic | - |
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