Monitoring the distribution of prompt gamma rays in boron neutron capture therapy using a multiple-scattering Compton camera: A Monte Carlo simulation study
DC Field | Value | Language |
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dc.contributor.author | Lee, Taewoong | - |
dc.contributor.author | Lee, Hyounggun | - |
dc.contributor.author | Lee, Wonho | - |
dc.date.accessioned | 2021-09-04T11:22:33Z | - |
dc.date.available | 2021-09-04T11:22:33Z | - |
dc.date.created | 2021-06-10 | - |
dc.date.issued | 2015-10-21 | - |
dc.identifier.issn | 0168-9002 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/92174 | - |
dc.description.abstract | This study evaluated the use of Compton imaging technology to monitor prompt gamma rays emitted by 10B in boron neutron capture therapy (BNCT) applied to a computerized human phantom. The Monte Carlo method, including particle-tracking techniques, was used for simulation. The distribution of prompt gamma rays emitted by the phantom during irradiation with neutron beams is closely associated with the distribution of the boron in the phantom. Maximum likelihood expectation maximization (MLEM) method was applied to the information obtained from the detected prompt gamma rays to reconstruct the distribution of the tumor including the boron uptake regions (BURs). The reconstructed Compton images of the prompt gamma rays were combined with the cross-sectional images of the human phantom. Quantitative analysis of the intensity curves showed that all combined images matched the predetermined conditions of the simulation. The tumors including the BURs were distinguishable if they were more than 2 cm apart. (C) 2015 Elsevier B.V. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.subject | MAXIMUM-LIKELIHOOD | - |
dc.subject | EM ALGORITHM | - |
dc.subject | BNCT | - |
dc.subject | SYSTEM | - |
dc.subject | RECONSTRUCTION | - |
dc.subject | DETECTORS | - |
dc.subject | PHANTOMS | - |
dc.subject | IMAGES | - |
dc.subject | SPECT | - |
dc.subject | BEAMS | - |
dc.title | Monitoring the distribution of prompt gamma rays in boron neutron capture therapy using a multiple-scattering Compton camera: A Monte Carlo simulation study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Wonho | - |
dc.identifier.doi | 10.1016/j.nima.2015.07.038 | - |
dc.identifier.scopusid | 2-s2.0-84955260873 | - |
dc.identifier.wosid | 000360933600019 | - |
dc.identifier.bibliographicCitation | NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, v.798, pp.135 - 139 | - |
dc.relation.isPartOf | NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT | - |
dc.citation.title | NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT | - |
dc.citation.volume | 798 | - |
dc.citation.startPage | 135 | - |
dc.citation.endPage | 139 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Instruments & Instrumentation | - |
dc.relation.journalResearchArea | Nuclear Science & Technology | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Instruments & Instrumentation | - |
dc.relation.journalWebOfScienceCategory | Nuclear Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Physics, Nuclear | - |
dc.relation.journalWebOfScienceCategory | Physics, Particles & Fields | - |
dc.subject.keywordPlus | MAXIMUM-LIKELIHOOD | - |
dc.subject.keywordPlus | EM ALGORITHM | - |
dc.subject.keywordPlus | BNCT | - |
dc.subject.keywordPlus | SYSTEM | - |
dc.subject.keywordPlus | RECONSTRUCTION | - |
dc.subject.keywordPlus | DETECTORS | - |
dc.subject.keywordPlus | PHANTOMS | - |
dc.subject.keywordPlus | IMAGES | - |
dc.subject.keywordPlus | SPECT | - |
dc.subject.keywordPlus | BEAMS | - |
dc.subject.keywordAuthor | Multiple scattering Compton camera (MSCC) | - |
dc.subject.keywordAuthor | Boron neutron capture therapy (BNCT) | - |
dc.subject.keywordAuthor | Born uptake regions (BURs) | - |
dc.subject.keywordAuthor | Prompt gamma-ray | - |
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