The Prevalence Rate of Tuberculin Skin Test Positive by Contacts Group to Predict the Development of Active Tuberculosis After School Outbreaks
DC Field | Value | Language |
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dc.contributor.author | Kim, Hee Jin | - |
dc.contributor.author | Chun, Byung Chul | - |
dc.contributor.author | Kwon, Amy M. | - |
dc.contributor.author | Lee, Gyeong-Ho | - |
dc.contributor.author | Ryu, Sungweon | - |
dc.contributor.author | Oh, Soo Yeon | - |
dc.contributor.author | Lee, Jin Beom | - |
dc.contributor.author | Yoo, Se Hwa | - |
dc.contributor.author | Kim, Eui Sook | - |
dc.contributor.author | Kim, Je Hyeong | - |
dc.contributor.author | Shin, Chol | - |
dc.contributor.author | Lee, Seung Heon | - |
dc.date.accessioned | 2021-09-04T12:04:25Z | - |
dc.date.available | 2021-09-04T12:04:25Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2015-10 | - |
dc.identifier.issn | 1738-3536 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/92354 | - |
dc.description.abstract | Background: The tuberculin skin test (TST) is the standard tool to diagnose latent tuberculosis infection (LTBI) in mass screening. The aim of this study is to find an optimal cut-off point of the TST+ rate within tuberculosis (TB) contacts to predict the active TB development among adolescents in school TB outbreaks. Methods: The Korean National Health Insurance Review and Assessment database was used to identify active TB development in relation to the initial TST (cut-off, 10 mm). The 7,475 contacts in 89 schools were divided into two groups: Incident TB group (43 schools) and no incident TB group (46 schools). LTBI treatment was initiated in 607 of the 1,761 TST+ contacts. The association with active TB progression was examined at different cut-off points of the TST+ rate. Results: The mean duration of follow-up was 3.9 +/- 0.9 years. Thirty-three contacts developed active TB during the 4,504 person-years among the TST+ contacts without LTBI treatment (n=1,154). The average TST+ rate for the incident TB group (n=43) and no incident TB group (n=46) were 31.0% and 15.5%, respectively. The TST+ rate per group was related with TB progression (odds ratio [OR], 1.025; 95% confidence interval [CI], 1.001-1.050; p=0.037). Based on the TST+ rate per group, active TB was best predicted at TST+ >= 16% ( OR, 3.11; 95% CI, 1.29-7.51; area under curve, 0.64). Conclusion: Sixteen percent of the TST+ rate per group within the same grade students can be suggested as an optimal cut-off to predict active TB development in middle and high schools TB outbreaks. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | TAEHAN KYORHAEK HYOPHOE-KOREAN ACAD TUBERCULOSIS & RESPIRATORY DISEASES | - |
dc.title | The Prevalence Rate of Tuberculin Skin Test Positive by Contacts Group to Predict the Development of Active Tuberculosis After School Outbreaks | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Chun, Byung Chul | - |
dc.contributor.affiliatedAuthor | Kwon, Amy M. | - |
dc.contributor.affiliatedAuthor | Shin, Chol | - |
dc.contributor.affiliatedAuthor | Lee, Seung Heon | - |
dc.identifier.doi | 10.4046/trd.2015.78.4.349 | - |
dc.identifier.scopusid | 2-s2.0-84953750892 | - |
dc.identifier.wosid | 000420540400007 | - |
dc.identifier.bibliographicCitation | TUBERCULOSIS AND RESPIRATORY DISEASES, v.78, no.4, pp.349 - 355 | - |
dc.relation.isPartOf | TUBERCULOSIS AND RESPIRATORY DISEASES | - |
dc.citation.title | TUBERCULOSIS AND RESPIRATORY DISEASES | - |
dc.citation.volume | 78 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 349 | - |
dc.citation.endPage | 355 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002035682 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Respiratory System | - |
dc.relation.journalWebOfScienceCategory | Respiratory System | - |
dc.subject.keywordAuthor | Adolescent | - |
dc.subject.keywordAuthor | Disease Outbreaks | - |
dc.subject.keywordAuthor | Tuberculin Test | - |
dc.subject.keywordAuthor | Latent Tuberculosis | - |
dc.subject.keywordAuthor | Tuberculosis | - |
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