Long-Term Clinical Outcomes of True and Non-True Bifurcation Lesions According to Medina Classification - Results From the COBIS (COronary BIfurcation Stent) II Registry
- Authors
- Park, Taek Kyu; Park, Yong Hwan; Song, Young Bin; Oh, Ju Hyeon; Chun, Woo Jung; Kang, Gu Hyun; Jang, Woo Jin; Hahn, Joo-Yong; Yang, Jeong Hoon; Choi, Seung-Hyuk; Choi, Jin-Ho; Lee, Sang Hoon; Jeong, Myung-Ho; Kim, Hyo-Soo; Lee, Jae-Hwan; Yu, Cheol Woong; Rha, Seung Woon; Jang, Yangsoo; Yoon, Jung Han; Tahk, Seung-Jea; Seung, Ki Bae; Park, Jong-Seon; Gwon, Hyeon-Cheol
- Issue Date
- 9월-2015
- Publisher
- JAPANESE CIRCULATION SOC
- Keywords
- Angioplasty; Medina classification; True bifurcation lesion
- Citation
- CIRCULATION JOURNAL, v.79, no.9, pp.1954 - U282
- Indexed
- SCIE
SCOPUS
- Journal Title
- CIRCULATION JOURNAL
- Volume
- 79
- Number
- 9
- Start Page
- 1954
- End Page
- U282
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/92574
- DOI
- 10.1253/circj.CJ-15-0264
- ISSN
- 1346-9843
- Abstract
- Background: Little is known about the clinical outcomes of patients with different types of coronary bifurcation lesions. We sought to compare long-term clinical outcomes of patients with true or non-true bifurcation lesions who underwent percutaneous coronary intervention. Methods and Results: We compared major adverse cardiac events (MACE: cardiac death, myocardial infarction [MI], or target lesion revascularization) between 1,502 patients with true bifurcation lesions (51.8%) and 1,395 with non-true bifurcation lesions (48.2%). True bifurcation lesions were defined as Medina classification (1.1.1), (1.0.1), or (0.1.1) lesions. During a median follow-up of 36 months, MACE occurred in 296 (10.2%) patients. Patients with true bifurcation lesions had a significantly higher risk of MACE than those with non-true bifurcation lesions (HR 1.39; 95% CI 1.08-1.80; P= 0.01). Among true bifurcation lesions, Medina (1.1.1) and (0.1.1) were associated with a higher risk of cardiac death or MI than Medina (1.0.1) (HR 4.15; 95% CI 1.01-17.1; P= 0.05). During the procedure, side branch occlusion occurred more frequently in Medina (1.1.1) and (1.0.1) than Medina (0.1.1) lesions (11.5% vs. 7.4%, P= 0.03). Conclusions: Patients with true bifurcation lesions had worse clinical outcomes than those with non-true bifurcation lesions. Procedural and long-term clinical outcomes differed according to the type of bifurcation lesion. These findings should be considered in future bifurcation studies.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
- Graduate School > Department of Biomedical Sciences > 1. Journal Articles
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