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Tunable sheathless microfluidic focusing using ion concentration polarization

Authors
Yoon, JunghyoCho, YoungkyuLee, Jeong HoonChung, Seok
Issue Date
24-8월-2015
Publisher
AMER INST PHYSICS
Citation
APPLIED PHYSICS LETTERS, v.107, no.8
Indexed
SCIE
SCOPUS
Journal Title
APPLIED PHYSICS LETTERS
Volume
107
Number
8
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/92734
DOI
10.1063/1.4929816
ISSN
0003-6951
Abstract
In this study, we developed a tunable sheathiess focusing method for focusing micrometer- and nanometer-sized particles, using ion concentration polarization (ICP) in an ion-selective, resin-coated channel. The particle movement was regulated using an electric field, and by varying the flow rate and ionic strength of the liquid solution; various phenomena were observed, depending on the particle properties. Here, we provide insights into the physical basis of the ICP-focusing phenomena, and a statistical approach for analyzing the particle movement. This ICP-focusing technology is an approach that could be applied for the separation and sorting of various particles, including cells, proteins, and bacteria. (C) 2015 AIP Publishing LLC.
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