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THE VALIDITY OF THE MOOD DISORDER QUESTIONNAIRE FOR SCREENING BIPOLAR DISORDER: A META-ANALYSIS

Authors
Wang, Hee RyungWoo, Young SupAhn, Hyeong SikAhn, Il MinKim, Hyun JungBahk, Won-Myong
Issue Date
7월-2015
Publisher
WILEY
Keywords
bipolar disorder; depression; mood disorders; assessment; diagnosis; measurement; psychometrics
Citation
DEPRESSION AND ANXIETY, v.32, no.7, pp.527 - 538
Indexed
SCIE
SSCI
SCOPUS
Journal Title
DEPRESSION AND ANXIETY
Volume
32
Number
7
Start Page
527
End Page
538
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/93111
DOI
10.1002/da.22374
ISSN
1091-4269
Abstract
We conducted a meta-analysis to review the diagnostic accuracy of the Mood Disorder Questionnaire (MDQ) among patients with mood disorders. We used a bivariate random effects model to calculate summary sensitivity and specificity. Twenty-one studies were included. At the standard or modified cutoff value of 7, summary sensitivity was .62 and summary specificity was .85. When we pooled 11 studies including both patients with bipolar disorder (BD) and those with unipolar depression, the summary sensitivity was .76 and summary specificity was .81. However, among the six studies that excluded patients with known BD, the summary sensitivity was significantly reduced to .37 and summary specificity was .88. There were no significant differences on the diagnostic accuracy of the MDQ between studies from Eastern and Western countries after adjusting for various clinical correlates. The overall diagnostic accuracy of the MDQ was relatively good. However, when the MDQ is applied among patients with depression without previous diagnoses of BD, its sensitivity was significantly reduced. This suggests that when the MDQ is applied among this population, its optimal cutoff value should be adjusted to enhance its sensitivity. (C) 2015 Wiley Periodicals, Inc.
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