Effect of levitra on sustenance of erection (EROS): an open-label, prospective, multicenter, single-arm study to investigate erection duration measured by stopwatch with flexible dose vardenafil administered for 8 weeks in subjects with erectile dysfunction
DC Field | Value | Language |
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dc.contributor.author | Shin, Y. S. | - |
dc.contributor.author | Lee, S. W. | - |
dc.contributor.author | Park, K. | - |
dc.contributor.author | Chung, W. S. | - |
dc.contributor.author | Kim, S. W. | - |
dc.contributor.author | Hyun, J. S. | - |
dc.contributor.author | Moon, D. G. | - |
dc.contributor.author | Yang, S-K | - |
dc.contributor.author | Ryu, J. K. | - |
dc.contributor.author | Yang, D. Y. | - |
dc.contributor.author | Moon, K. H. | - |
dc.contributor.author | Min, K. S. | - |
dc.contributor.author | Park, J. K. | - |
dc.date.accessioned | 2021-09-04T16:51:02Z | - |
dc.date.available | 2021-09-04T16:51:02Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2015-05 | - |
dc.identifier.issn | 0955-9930 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/93760 | - |
dc.description.abstract | To investigate the change of erection duration measured by stopwatch with flexible dose vardenafil administered for 8 weeks in subjects with erectile dysfunction (ED). Effect of levitra on sustenance of erection was an open-label, prospective, multicenter and single-arm study designed to measure the duration of erection in men with ED receiving a flexible dose of vardenafil over an 8-week treatment period. Patients were instructed to take vardenafil 10 mg 60 min before attempting the intercourse. Vardenfil could be increased to 20 mg or decreased to 5 mg concerning patients' efficacy and safety. Following the initial screening, patients entered a 4-week treatment-free run-in phase and 8-week treatment period, during which they were instructed to attempt intercourse at least four times on four separate days. A total of 95 men were enrolled in 10 centers. After the 8 weeks treatment, the mean duration of erection leading to successful intercourse was statistically superior when patients were treated with vardenafil. After an 8-week treatment, the duration of erection leading to successful intercourse was 9.39 min. There were significant benefits with vardenafil in all domains of International Index of Erectile Function. Secondary efficacy end points included success rate of penetration, maintaining erection, ejaculation and satisfaction were superior when patients were treated with vardenafil. There was a significant correlation between duration of erection with other sexual factors. Also partner's sexual satisfaction was increased with vardenafil. Most adverse events were mild or moderate in severity. Vardenafil was safe and well tolerated. Vardenafil therapy provided a statistically superior duration of erection leading to successful intercourse in men with ED with female partner. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | NATURE PUBLISHING GROUP | - |
dc.subject | PLACEBO-CONTROLLED TRIAL | - |
dc.subject | DOUBLE-BLIND | - |
dc.subject | TREATMENT SATISFACTION | - |
dc.subject | FEMALE PARTNERS | - |
dc.subject | MEN | - |
dc.subject | EFFICACY | - |
dc.subject | LIFE | - |
dc.subject | IMPROVEMENT | - |
dc.subject | TOLERABILITY | - |
dc.subject | THERAPY | - |
dc.title | Effect of levitra on sustenance of erection (EROS): an open-label, prospective, multicenter, single-arm study to investigate erection duration measured by stopwatch with flexible dose vardenafil administered for 8 weeks in subjects with erectile dysfunction | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Moon, D. G. | - |
dc.identifier.doi | 10.1038/ijir.2014.39 | - |
dc.identifier.scopusid | 2-s2.0-84929267067 | - |
dc.identifier.wosid | 000354418800004 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH, v.27, no.3, pp.95 - 102 | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH | - |
dc.citation.title | INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH | - |
dc.citation.volume | 27 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 95 | - |
dc.citation.endPage | 102 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Urology & Nephrology | - |
dc.relation.journalWebOfScienceCategory | Urology & Nephrology | - |
dc.subject.keywordPlus | PLACEBO-CONTROLLED TRIAL | - |
dc.subject.keywordPlus | DOUBLE-BLIND | - |
dc.subject.keywordPlus | TREATMENT SATISFACTION | - |
dc.subject.keywordPlus | FEMALE PARTNERS | - |
dc.subject.keywordPlus | MEN | - |
dc.subject.keywordPlus | EFFICACY | - |
dc.subject.keywordPlus | LIFE | - |
dc.subject.keywordPlus | IMPROVEMENT | - |
dc.subject.keywordPlus | TOLERABILITY | - |
dc.subject.keywordPlus | THERAPY | - |
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