Endoplasmic reticulum aminopeptidase 2 is highly expressed in papillary thyroid microcarcinoma with cervical lymph node metastasis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Woo Young | - |
dc.contributor.author | Lee, Jae Bok | - |
dc.contributor.author | Kim, Hoon Yub | - |
dc.contributor.author | Woo, Sang Uk | - |
dc.contributor.author | Son, Gil Soo | - |
dc.contributor.author | Bae, Jeoung Won | - |
dc.date.accessioned | 2021-09-04T17:30:51Z | - |
dc.date.available | 2021-09-04T17:30:51Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2015-04 | - |
dc.identifier.issn | 0973-1482 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/93888 | - |
dc.description.abstract | Background: The cervical lymph node metastasis (CLNM) of papillary thyroid microcarcinoma (PTMC) is not uncommon. However, prophylactic cervical lymph node dissection in all PTMC is debatable. Molecular markers of predicting CLNM would help to decide to either do or not do cervical lymph node dissection which might increase morbidities. Aims: We aimed to characterize gene expression profiles and molecular markers of CLNM in PTMC. Settings and Design: The thyroid frozen tissues were obtained with from six PTMC patients, who underwent total thyroidectomy. Methods: We performed oligonucleotide microarray analysis with three PTMCs with CLNM and three without CLNM. Real-time quantitative reverse transcription-polymerase chain reaction was used to validate the gene. Statistical Analysis Used: We used linear models for microarray data. Results: We identified 12 differentially expressed gene, and most one is endoplasmic reticulum aminopeptidase 2 (ERAP2). Conclusion: ERAP2 might be associated with CLNM in PTMC. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | MEDKNOW PUBLICATIONS & MEDIA PVT LTD | - |
dc.subject | ERAP2 | - |
dc.subject | OXYTOCINASE | - |
dc.subject | CARCINOMA | - |
dc.subject | CANCER | - |
dc.subject | CELLS | - |
dc.title | Endoplasmic reticulum aminopeptidase 2 is highly expressed in papillary thyroid microcarcinoma with cervical lymph node metastasis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Woo Young | - |
dc.contributor.affiliatedAuthor | Lee, Jae Bok | - |
dc.contributor.affiliatedAuthor | Kim, Hoon Yub | - |
dc.contributor.affiliatedAuthor | Woo, Sang Uk | - |
dc.contributor.affiliatedAuthor | Son, Gil Soo | - |
dc.contributor.affiliatedAuthor | Bae, Jeoung Won | - |
dc.identifier.doi | 10.4103/0973-1482.146060 | - |
dc.identifier.scopusid | 2-s2.0-84937112842 | - |
dc.identifier.wosid | 000357935800038 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, v.11, no.2, pp.443 - 446 | - |
dc.relation.isPartOf | JOURNAL OF CANCER RESEARCH AND THERAPEUTICS | - |
dc.citation.title | JOURNAL OF CANCER RESEARCH AND THERAPEUTICS | - |
dc.citation.volume | 11 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 443 | - |
dc.citation.endPage | 446 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.subject.keywordPlus | ERAP2 | - |
dc.subject.keywordPlus | OXYTOCINASE | - |
dc.subject.keywordPlus | CARCINOMA | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordAuthor | Lymph nodes | - |
dc.subject.keywordAuthor | metastasis | - |
dc.subject.keywordAuthor | microarray analysis | - |
dc.subject.keywordAuthor | thyroid neoplasm | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
145 Anam-ro, Seongbuk-gu, Seoul, 02841, Korea+82-2-3290-2963
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.