Usefulness of permutation entropy as an anesthetic depth indicator in children
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Pil-Jong | - |
dc.contributor.author | Kim, Hong-Gee | - |
dc.contributor.author | Noh, Gyu-Jeong | - |
dc.contributor.author | Koo, Yong-Seo | - |
dc.contributor.author | Shin, Teo Jeon | - |
dc.date.accessioned | 2021-09-04T17:41:14Z | - |
dc.date.available | 2021-09-04T17:41:14Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2015-04 | - |
dc.identifier.issn | 1567-567X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/93960 | - |
dc.description.abstract | Permutation entropy (PE) as a complexity measure has been introduced to monitor anesthetic depth for adult. However, PE has not yet been evaluated for its clinical applicability as an indicator of anesthetic depth in children. Therefore, in order to investigate the validity of PE, we compared PE with BIS using pharmacodynamic (PD) modeling in children. Electroencephalogram (EEG) was obtained from BIS monitor during sevoflurane deepening and lightening protocol. End-tidal sevoflurane concentration (Etsevo) and BIS were measured simultaneously. PE was calculated from the processed EEG with the scale ranging from 0 to 100. NONMEM software was used to investigate the PD relationship between Etsevo with BIS and PE. Adjusted PE (APE) values were decreased as anesthesia deepened. APE and BIS showed significant linear correlation (P < 0.001), indicating that PE also reflects anesthesia depth. PD parameters for APE and BIS were estimated with a sigmoid Emax model which describes the relationship between Etsevo and APE/BIS (E (o) : 78, E (max) : 17.6, C (e50) : 2.5 vol%; gamma: 13.1, k (eo) : 0.47 min(-1) for APE; E (o) : 89.4; E (max) : 15.7; C (e50) : 2.2 vol%; gamma: 6.6, k(eo): 0.52 min(-1) for BIS). PE seems to be a useful indicator of anesthetic depth, which is comparable to BIS in children. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER/PLENUM PUBLISHERS | - |
dc.subject | BISPECTRAL INDEX | - |
dc.subject | APPROXIMATE ENTROPY | - |
dc.subject | EEG SIGNAL | - |
dc.subject | ELECTROENCEPHALOGRAM | - |
dc.subject | SEVOFLURANE | - |
dc.subject | AGE | - |
dc.title | Usefulness of permutation entropy as an anesthetic depth indicator in children | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Koo, Yong-Seo | - |
dc.identifier.doi | 10.1007/s10928-015-9405-5 | - |
dc.identifier.scopusid | 2-s2.0-84925538384 | - |
dc.identifier.wosid | 000351172300003 | - |
dc.identifier.bibliographicCitation | JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS, v.42, no.2, pp.123 - 134 | - |
dc.relation.isPartOf | JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS | - |
dc.citation.title | JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS | - |
dc.citation.volume | 42 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 123 | - |
dc.citation.endPage | 134 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.subject.keywordPlus | BISPECTRAL INDEX | - |
dc.subject.keywordPlus | APPROXIMATE ENTROPY | - |
dc.subject.keywordPlus | EEG SIGNAL | - |
dc.subject.keywordPlus | ELECTROENCEPHALOGRAM | - |
dc.subject.keywordPlus | SEVOFLURANE | - |
dc.subject.keywordPlus | AGE | - |
dc.subject.keywordAuthor | Anesthesia | - |
dc.subject.keywordAuthor | Entropy | - |
dc.subject.keywordAuthor | NONMEM | - |
dc.subject.keywordAuthor | Sevoflurane | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.