Management of hepatocellular carcinoma with portal vein thrombosis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Quirk, Matthew | - |
dc.contributor.author | Kim, Yun Hwan | - |
dc.contributor.author | Saab, Sammy | - |
dc.contributor.author | Lee, Edward Wolfgang | - |
dc.date.accessioned | 2021-09-04T18:02:50Z | - |
dc.date.available | 2021-09-04T18:02:50Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2015-03-28 | - |
dc.identifier.issn | 1007-9327 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/94086 | - |
dc.description.abstract | Management of hepatocellular carcinoma (HCC) with portal vein thrombosis (PVT) is complex and requires an understanding of multiple therapeutic options. PVT is present in 10%-40% of HCC at the time of diagnosis, and is an adverse prognostic factor. Management options are limited, as transplantation is generally contraindicated, and surgical resection is only rarely performed in select centers. Systemic medical therapy with sorafenib has been shown to modestly prolong survival. Transarterial chemoembolization has been performed in select cases but has shown a high incidence of complications. Emerging data on treatment of PVT with Y-90 radioembolization suggest that this modality is well-tolerated and associated with favorable overall survival. Current society guidelines do not yet specifically recommend radioembolization for patients with PVT, but this may change with the development of newer staging systems and treatment algorithms. In this comprehensive literature review, we present current and available management options with the relative advantages, disadvantages and contraindications of these treatment options with summarized data on overall survival. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | BAISHIDENG PUBLISHING GROUP INC | - |
dc.subject | TRANSCATHETER ARTERIAL CHEMOEMBOLIZATION | - |
dc.subject | CONCURRENT TRANSARTERIAL CHEMOEMBOLIZATION | - |
dc.subject | EXTERNAL-BEAM RADIOTHERAPY | - |
dc.subject | Y-90 GLASS MICROSPHERES | - |
dc.subject | FATTY LIVER-DISEASE | - |
dc.subject | LONG-TERM OUTCOMES | - |
dc.subject | TUMOR THROMBOSIS | - |
dc.subject | RADIATION-THERAPY | - |
dc.subject | PHASE-III | - |
dc.subject | NATURAL-HISTORY | - |
dc.title | Management of hepatocellular carcinoma with portal vein thrombosis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Yun Hwan | - |
dc.identifier.doi | 10.3748/wjg.v21.i12.3462 | - |
dc.identifier.scopusid | 2-s2.0-84926341363 | - |
dc.identifier.wosid | 000351858600002 | - |
dc.identifier.bibliographicCitation | WORLD JOURNAL OF GASTROENTEROLOGY, v.21, no.12, pp.3462 - 3471 | - |
dc.relation.isPartOf | WORLD JOURNAL OF GASTROENTEROLOGY | - |
dc.citation.title | WORLD JOURNAL OF GASTROENTEROLOGY | - |
dc.citation.volume | 21 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 3462 | - |
dc.citation.endPage | 3471 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.subject.keywordPlus | TRANSCATHETER ARTERIAL CHEMOEMBOLIZATION | - |
dc.subject.keywordPlus | CONCURRENT TRANSARTERIAL CHEMOEMBOLIZATION | - |
dc.subject.keywordPlus | EXTERNAL-BEAM RADIOTHERAPY | - |
dc.subject.keywordPlus | Y-90 GLASS MICROSPHERES | - |
dc.subject.keywordPlus | FATTY LIVER-DISEASE | - |
dc.subject.keywordPlus | LONG-TERM OUTCOMES | - |
dc.subject.keywordPlus | TUMOR THROMBOSIS | - |
dc.subject.keywordPlus | RADIATION-THERAPY | - |
dc.subject.keywordPlus | PHASE-III | - |
dc.subject.keywordPlus | NATURAL-HISTORY | - |
dc.subject.keywordAuthor | Hepatocellular carcinoma | - |
dc.subject.keywordAuthor | Portal vein thrombosis | - |
dc.subject.keywordAuthor | Yttrium 90 | - |
dc.subject.keywordAuthor | Selective internal radiation therapy | - |
dc.subject.keywordAuthor | Management | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.