An IgE-Mediated Allergic Reaction Caused by Mulberry Fruit
DC Field | Value | Language |
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dc.contributor.author | Choi, Jong Hyun | - |
dc.contributor.author | Sim, Jae Kyoem | - |
dc.contributor.author | Oh, Jee Youn | - |
dc.contributor.author | Hur, Gyu-Young | - |
dc.contributor.author | Min, Kyung Hoon | - |
dc.contributor.author | Lee, Sung Yong | - |
dc.contributor.author | Shim, Jae Jeong | - |
dc.contributor.author | Kang, Kyung Ho | - |
dc.date.accessioned | 2021-09-04T18:31:31Z | - |
dc.date.available | 2021-09-04T18:31:31Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2015-03 | - |
dc.identifier.issn | 2092-7355 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/94198 | - |
dc.description.abstract | Mulberry (Morus spp.) is a widespread deciduous tree and its fruit is commonly eaten in Korea and eastern Asia. Some reports demonstrate that mulberry fruit is a food allergen in the Mediterranean area. However, there has been no report of systemic allergic reactions after ingesting mulberry fruit in Korea. An 18-year-old boy with a mulberry fruit allergy visited our allergy clinic. He had experienced generalized urticaria, chest tightness, breathing difficulty, and abdominal cramping after ingesting mulberry fruit. The patient had a positive skin reaction to mulberry fruit extract (mean wheal size, 5 mm). We performed an ELISA to detect specific IgE antibody (Ab) to mulberry fruit extract in the patient's serum compared to those of non-atopic healthy controls and birch-sensitized individuals. Specific IgE Ab to mulberry fruit extract was detected in the patient's serum, as compared to non-atopic healthy controls. Another subject, who was strongly sensitized to birch pollen, also had a positive serum-specific IgE Ab to mulberry fruit. We performed IgE immunoblot analysis using the patient's and the other subject's sera, who had serum-specific IgE to mulberry fruit, to identify the IgE-binding component. An identical IgE-binding component to mulberry extract was detected in the two subjects at around 17 kDa, and which might be PR 10 of Bet v 1. In conclusion, mulberry fruit could induce a systemic allergic reaction through an IgE-mediated mechanism, and cross-reactivity might occur between mulberry fruit and birch pollen. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN ACAD ASTHMA ALLERGY & CLINICAL IMMUNOLOGY | - |
dc.subject | PATHOGENESIS-RELATED PROTEINS | - |
dc.subject | POLLEN | - |
dc.subject | FOOD | - |
dc.subject | PREVALENCE | - |
dc.title | An IgE-Mediated Allergic Reaction Caused by Mulberry Fruit | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Hur, Gyu-Young | - |
dc.contributor.affiliatedAuthor | Min, Kyung Hoon | - |
dc.contributor.affiliatedAuthor | Lee, Sung Yong | - |
dc.contributor.affiliatedAuthor | Shim, Jae Jeong | - |
dc.contributor.affiliatedAuthor | Kang, Kyung Ho | - |
dc.identifier.doi | 10.4168/aair.2015.7.2.195 | - |
dc.identifier.scopusid | 2-s2.0-84937919154 | - |
dc.identifier.wosid | 000358824400014 | - |
dc.identifier.bibliographicCitation | ALLERGY ASTHMA & IMMUNOLOGY RESEARCH, v.7, no.2, pp.195 - 198 | - |
dc.relation.isPartOf | ALLERGY ASTHMA & IMMUNOLOGY RESEARCH | - |
dc.citation.title | ALLERGY ASTHMA & IMMUNOLOGY RESEARCH | - |
dc.citation.volume | 7 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 195 | - |
dc.citation.endPage | 198 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001963114 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Allergy | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalWebOfScienceCategory | Allergy | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.subject.keywordPlus | PATHOGENESIS-RELATED PROTEINS | - |
dc.subject.keywordPlus | POLLEN | - |
dc.subject.keywordPlus | FOOD | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordAuthor | Mulberry | - |
dc.subject.keywordAuthor | allergen | - |
dc.subject.keywordAuthor | food allergy | - |
dc.subject.keywordAuthor | IgE | - |
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