Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Incidence and Natural Course of Inflammatory Bowel Disease in Korea, 2006-2012: A Nationwide Population-based Study

Authors
Kim, Hyun JungHann, Hoo JaeHong, Sung NoKim, Kyoung HoonAhn, Il MinSong, Ji YangLee, Sang HyukAhn, Hyeong Sik
Issue Date
3월-2015
Publisher
OXFORD UNIV PRESS INC
Keywords
epidemiology; bowel resection; mortality; ulcerative colitis; Crohn' s disease; Korea
Citation
INFLAMMATORY BOWEL DISEASES, v.21, no.3, pp.623 - 630
Indexed
SCIE
SCOPUS
Journal Title
INFLAMMATORY BOWEL DISEASES
Volume
21
Number
3
Start Page
623
End Page
630
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/94306
DOI
10.1097/MIB.0000000000000313
ISSN
1078-0998
Abstract
Background:Although a rising trend in the incidence of inflammatory bowel disease (IBD) in Asia has been recognized, national-level, population-based studies are lacking. In this study, we investigate the epidemiological features and natural course of IBD in Korea, including incidence, bowel resection rates, survival, and cause of death.Methods:We analyzed the Rare Intractable Disease registration and Health Insurance Review and Assessment Services claims database, which include information on every patients with IBD diagnosed through uniform criteria from 2006 to 2012. Twenty-seven thousand four hundred nineteen patients with IBD newly diagnosed from 2006 to 2012 were traced to bowel resection, survival, and cause of death.Results:During study period, mean annual incidence for ulcerative colitis was 4.6 per 10(5) and for Crohn's disease (CD) was 3.2 per 10(5). Bowel resection rates at 1 and 5 years for patients with ulcerative colitis were 0.8% and 2.1%, respectively, and for patients with CD were 5.0% and 9.1%, respectively. Survival of patients with CD was lower than that of the general population, whereas patients with ulcerative colitis had similar survival. In patients with CD, mortality for colon cancer, lung cancer, and gastrointestinal disease was significantly increased compared with general population.Conclusions:Incidence of IBD found in our study is the highest in East Asia. Lower bowel resection rates and higher survival compared to those of Western nations suggest that the natural course of IBD may be different between East Asia and the West.
Files in This Item
There are no files associated with this item.
Appears in
Collections
Graduate School > Department of Biomedical Sciences > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Altmetrics

Total Views & Downloads

BROWSE