Hepatokines as a Link between Obesity and Cardiovascular Diseases
- Authors
- Yoo, Hye Jin; Choi, Kyung Mook
- Issue Date
- 2월-2015
- Publisher
- KOREAN DIABETES ASSOC
- Keywords
- Fetuin-A; Fibroblast growth factor 21; Hepatokines; Non-alcoholic fatty liver disease; Selenoprotein P
- Citation
- DIABETES & METABOLISM JOURNAL, v.39, no.1, pp.10 - 15
- Indexed
- SCOPUS
KCI
- Journal Title
- DIABETES & METABOLISM JOURNAL
- Volume
- 39
- Number
- 1
- Start Page
- 10
- End Page
- 15
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/94454
- DOI
- 10.4093/dmj.2015.39.1.10
- ISSN
- 2233-6079
- Abstract
- Non-alcoholic fatty liver disease, which is considered a hepatic manifestation of metabolic syndrome, independently increases the risks of developing cardiovascular disease (CVD) and type 2 diabetes mellitus. Recent emerging evidence suggests that a group of predominantly liver-derived proteins called hepatokines directly affect the progression of atherosclerosis by modulating endothelial dysfunction and infiltration of inflammatory cells into vessel walls. Here, we summarize the role of the representative hepatokines fibroblast growth factor 21, fetuin-A, and selenoprotein P in the progression of CVD.
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Collections - Graduate School > Department of Biomedical Sciences > 1. Journal Articles
- College of Medicine > Department of Medical Science > 1. Journal Articles
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