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Highly selective two-photon imaging of cysteine in cancerous cells and tissues

Authors
Lee, Yun HakRen, Wen XiuHan, JiyouSunwoo, KyoungLim, Ja-YunKim, Jong-HoonKim, Jong Seung
Issue Date
2015
Publisher
ROYAL SOC CHEMISTRY
Citation
CHEMICAL COMMUNICATIONS, v.51, no.76, pp.14401 - 14404
Indexed
SCIE
SCOPUS
Journal Title
CHEMICAL COMMUNICATIONS
Volume
51
Number
76
Start Page
14401
End Page
14404
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/96206
DOI
10.1039/c5cc06038a
ISSN
1359-7345
Abstract
Abnormal concentrations of Cys have been reported to be implicated in various health problems, including cancer, neuropathy, and cardiomyopathy. We present a novel two-photon fluorescent probe for the specific recognition of cysteine over homocysteine and glutathione, and the bioapplication of this probe for the imaging of live cancerous cells and thick tissues.
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