beta-Isocyanoalanine as an IR probe: comparison of vibrational dynamics between isonitrile and nitrile-derivatized IR probes
- Authors
- Maj, Michal; Ahn, Changwoo; Kossowska, Dorota; Park, Kwanghee; Kwak, Kyungwon; Han, Hogyu; Cho, Minhaeng
- Issue Date
- 2015
- Publisher
- ROYAL SOC CHEMISTRY
- Citation
- PHYSICAL CHEMISTRY CHEMICAL PHYSICS, v.17, no.17, pp.11770 - 11778
- Indexed
- SCIE
SCOPUS
- Journal Title
- PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- Volume
- 17
- Number
- 17
- Start Page
- 11770
- End Page
- 11778
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/96315
- DOI
- 10.1039/c5cp00454c
- ISSN
- 1463-9076
- Abstract
- An infrared (IR) probe based on isonitrile (NC)-derivatized alanine 1 was synthesized and the vibrational properties of its NC stretching mode were investigated using FTIR and femtosecond IR pump-probe spectroscopy. It is found that the NC stretching mode is very sensitive to the hydrogen-bonding ability of solvent molecules. Moreover, its transition dipole strength is larger than that of nitrile (CN) in nitrile-derivatized IR probe 2. The vibrational lifetime of the NC stretching mode is found to be 5.5 +/- 0.2 ps in both D2O and DMF solvents, which is several times longer than that of the azido (N-3) stretching mode in azido-derivatized IR probe 3. Altogether these properties suggest that the NC group can be a very promising sensing moiety of IR probes for studying the solvation structure and dynamics of biomolecules.
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- Appears in
Collections - College of Science > College of Science > 1. Journal Articles
- College of Science > Department of Chemistry > 1. Journal Articles
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