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A Carbazole Based Bimodal "Turn-On" Fluorescent Probe for Biothiols (Cysteine/Homocysteine) and Fluoride: Sensing, Imaging and its Applications
- Authors
- Kaur, Matinder; Yoon, Byungkwon; Kumar, Rajesh; Cho, Min Ju; Kim, Hak Joong; Kim, Jong Seung; Choi, Doug Hoon
- Issue Date
- 20-12월-2014
- Publisher
- WILEY-V C H VERLAG GMBH
- Keywords
- Carbazole probe; Cysteine/homocysteine sensing; Fluoride recognition; Molecular keypad lock; Bioimaging
- Citation
- BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.35, no.12, pp.3437 - 3442
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- BULLETIN OF THE KOREAN CHEMICAL SOCIETY
- Volume
- 35
- Number
- 12
- Start Page
- 3437
- End Page
- 3442
- ISSN
- 0253-2964
- Abstract
- A well-known carbazole-based precursor (probe 1) was used for the detection of cysteine/homocysteine and fluoride. Probe 1 shows a "turn-on" response to cysteine/homocysteine and fluoride via enhancement in emission intensity at 442 mu and 462 nm respectively, in solutions and living cells. Furthermore, probe 1 behaves as a fluorescent molecular switch between cysteine/homocysteine and fluoride as the chemical inputs, which have been used for the development of a combinatorial logic circuit and a molecular keypad lock.
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