Behavioral changes of zebrafish according to cisplatin-induced toxicity of the balance system
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, M. J. | - |
dc.contributor.author | Choi, J. | - |
dc.contributor.author | Kim, N. | - |
dc.contributor.author | Han, G. C. | - |
dc.date.accessioned | 2021-09-05T03:19:05Z | - |
dc.date.available | 2021-09-05T03:19:05Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2014-11 | - |
dc.identifier.issn | 0960-3271 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/96852 | - |
dc.description.abstract | Background and objectives: Zebrafish are commonly used as experimental animals in otolaryngology studies. However, the behavioral characteristics of these fish are not well known, especially those related to the vestibular system. The goal of this study was to evaluate behavioral changes in zebrafish due to toxicity in the balance system. Materials and methods: Zebrafish were exposed to 1000 M cisplatin for 6 h. We, then, periodically monitored swimming depth, total swimming distance, peak swimming velocity, and mean swimming velocity of the fish for approximately 21 days. Results: Total swimming distance (p < 0.0001), peak swimming velocity (p = 0.0063), and mean swimming velocity (p < 0.0001) in the cisplatin-administered group were significantly decreased when compared with control fish. Conclusion: Our findings demonstrate that cisplatin can alter the locomotion behavior of zebrafish. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | SAGE PUBLICATIONS LTD | - |
dc.subject | LATERAL-LINE FUNCTION | - |
dc.subject | AFFERENT NEURONS | - |
dc.subject | EYE-MOVEMENTS | - |
dc.subject | HAIR-CELLS | - |
dc.subject | INNER-EAR | - |
dc.subject | HEARING | - |
dc.subject | ORIGIN | - |
dc.title | Behavioral changes of zebrafish according to cisplatin-induced toxicity of the balance system | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Choi, J. | - |
dc.identifier.doi | 10.1177/0960327114521046 | - |
dc.identifier.scopusid | 2-s2.0-84910065884 | - |
dc.identifier.wosid | 000344349600009 | - |
dc.identifier.bibliographicCitation | HUMAN & EXPERIMENTAL TOXICOLOGY, v.33, no.11, pp.1167 - 1175 | - |
dc.relation.isPartOf | HUMAN & EXPERIMENTAL TOXICOLOGY | - |
dc.citation.title | HUMAN & EXPERIMENTAL TOXICOLOGY | - |
dc.citation.volume | 33 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 1167 | - |
dc.citation.endPage | 1175 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Toxicology | - |
dc.relation.journalWebOfScienceCategory | Toxicology | - |
dc.subject.keywordPlus | LATERAL-LINE FUNCTION | - |
dc.subject.keywordPlus | AFFERENT NEURONS | - |
dc.subject.keywordPlus | EYE-MOVEMENTS | - |
dc.subject.keywordPlus | HAIR-CELLS | - |
dc.subject.keywordPlus | INNER-EAR | - |
dc.subject.keywordPlus | HEARING | - |
dc.subject.keywordPlus | ORIGIN | - |
dc.subject.keywordAuthor | Zebrafish | - |
dc.subject.keywordAuthor | cisplatin | - |
dc.subject.keywordAuthor | toxicity | - |
dc.subject.keywordAuthor | vestibule of ear | - |
dc.subject.keywordAuthor | behavior | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.