Changes in Retinal Nerve Fiber Layer Thickness After Optic Disc Hemorrhage in Glaucomatous Eyes
- Authors
- Hwang, Young Hoon; Kim, Yong Yeon; Kim, Hwang Ki; Sohn, Yong Ho
- Issue Date
- 10월-2014
- Publisher
- LIPPINCOTT WILLIAMS & WILKINS
- Keywords
- glaucoma; optic disc hemorrhage; optical coherence tomography; retinal nerve fiber layer
- Citation
- JOURNAL OF GLAUCOMA, v.23, no.8, pp.547 - 552
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF GLAUCOMA
- Volume
- 23
- Number
- 8
- Start Page
- 547
- End Page
- 552
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/97335
- DOI
- 10.1097/IJG.0000000000000083
- ISSN
- 1057-0829
- Abstract
- Purpose: The aim of this study was to investigate the changes in longitudinal retinal nerve fiber layer thickness (RNFLT) as determined by spectral-domain optical coherence tomography (OCT) after optic disc hemorrhage (DH) in glaucomatous eyes. Methods: A total of 65 eyes with unilateral DH and 65 contralateral eyes without DH were subjected to RNFLT measurements by using OCT at the time of DH detection and at 1 year (12 +/- 2 mo) and 2 years (24 +/- 2 mo) later. For the definition of event-based significant RNFLT changes (a change beyond the upper limit of the 95% confidence interval of test-retest variability), 50 eyes with stable glaucoma without DH that had undergone OCT examinations 3 times with a 1-year interval were also enrolled. Clock-hour sector RNFLT in the eyes with DH and clock-hour sector RNFLT at equivalent locations in the contralateral eyes without DH were analyzed to assess localized and spatially compatible RNFLT changes associated with DH. Results: Of the eyes with DH, 38.5% showed decrease in RNFLT and 6.2% showed increase in RNFLT 1 year after DH detection, whereas 58.5% showed decrease in RNFLT and no eye showed increase in RNFLT 2 years after DH detection. Significant decreases in RNFLT in the eyes with DH were associated with the presence of recurrent DH and greater baseline RNFLT (P < 0.05). Of the contralateral eyes without DH, 4.6% and 15.4% showed decrease in RNFLT 1 and 2 years after DH detection, respectively. Conclusions: In the glaucomatous eyes, DH was associated with progressive decrease in RNFLT as determined by OCT, especially in the eyes with recurrent DH and greater baseline RNFLT.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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