Accuracy of lung nodule volumetry in low-dose CT with iterative reconstruction: an anthropomorphic thoracic phantom study
DC Field | Value | Language |
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dc.contributor.author | Doo, K. W. | - |
dc.contributor.author | Kang, E-Y | - |
dc.contributor.author | Yong, H. S. | - |
dc.contributor.author | Woo, O. H. | - |
dc.contributor.author | Lee, K. Y. | - |
dc.contributor.author | Oh, Y-W | - |
dc.date.accessioned | 2021-09-05T05:44:55Z | - |
dc.date.available | 2021-09-05T05:44:55Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2014-09 | - |
dc.identifier.issn | 0007-1285 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/97547 | - |
dc.description.abstract | Objective: The purpose of this study was to assess accuracy of lung nodule volumetry in low-dose CT with application of iterative reconstruction (IR) according to nodule size, nodule density and CT tube currents, using artificial lung nodules within an anthropomorphic thoracic phantom. Methods: Eight artificial nodules (four diameters: 5, 8, 10 and 12mm; two CT densities: -630HU that represents ground-glass nodule and +100HU that represents solid nodule) were randomly placed inside a thoracic phantom. Scans were performed with tube current-time product to 10, 20, 30 and 50mAs. Images were reconstructed with IR and filtered back projection (FBP). We compared volume estimates to a reference standard and calculated the absolute percentage error (APE). Results: The APE of all nodules was significantly lower when IR was used than with FBP (7.5 +/- 4.7% compared with 9.0 +/- 6.9%; p<0.001). The effect of IR was more pronounced for smaller nodules (p<0.001). IR showed a significantly lower APE than FBP in ground-glass nodules (p<0.0001), and the difference was more pronounced at the lowest tube current (11.8 +/- 5.9% compared with 21.3 +/- 6.1%; p<0.0001). The effect of IR was most pronounced for ground-glass nodules in the lowest CT tube current. Conclusion: Lung nodule volumetry in low-dose CT by application of IR showed reliable accuracy in a phantom study. Lung nodule volumetry can be reliably applicable to all lung nodules including small, ground-glass nodules even in ultra-low-dose CT with application of IR. Advances in knowledge: IR significantly improved the accuracy of lung nodule volumetry compared with FBP particularly for ground-glass (-630HU) nodules. Volumetry in low-dose CT can be utilized in patient with lung nodule work-up, and IR has benefit for small, ground-glass lung nodules in low-dose CT. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | BRITISH INST RADIOLOGY | - |
dc.subject | FILTERED BACK-PROJECTION | - |
dc.subject | PULMONARY NODULES | - |
dc.subject | COMPUTED-TOMOGRAPHY | - |
dc.subject | DOUBLING TIMES | - |
dc.subject | IMAGE QUALITY | - |
dc.subject | SOLID TUMORS | - |
dc.subject | CHEST CT | - |
dc.subject | REDUCTION | - |
dc.subject | VARIABILITY | - |
dc.subject | ANGIOGRAPHY | - |
dc.title | Accuracy of lung nodule volumetry in low-dose CT with iterative reconstruction: an anthropomorphic thoracic phantom study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kang, E-Y | - |
dc.contributor.affiliatedAuthor | Woo, O. H. | - |
dc.identifier.doi | 10.1259/bjr.20130644 | - |
dc.identifier.scopusid | 2-s2.0-84907481886 | - |
dc.identifier.wosid | 000341309700002 | - |
dc.identifier.bibliographicCitation | BRITISH JOURNAL OF RADIOLOGY, v.87, no.1041 | - |
dc.relation.isPartOf | BRITISH JOURNAL OF RADIOLOGY | - |
dc.citation.title | BRITISH JOURNAL OF RADIOLOGY | - |
dc.citation.volume | 87 | - |
dc.citation.number | 1041 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | FILTERED BACK-PROJECTION | - |
dc.subject.keywordPlus | PULMONARY NODULES | - |
dc.subject.keywordPlus | COMPUTED-TOMOGRAPHY | - |
dc.subject.keywordPlus | DOUBLING TIMES | - |
dc.subject.keywordPlus | IMAGE QUALITY | - |
dc.subject.keywordPlus | SOLID TUMORS | - |
dc.subject.keywordPlus | CHEST CT | - |
dc.subject.keywordPlus | REDUCTION | - |
dc.subject.keywordPlus | VARIABILITY | - |
dc.subject.keywordPlus | ANGIOGRAPHY | - |
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