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A Case of Mental Retardation with Paraphilia Treated with Depot Leuprorelin

Authors
Park, Woo SungKim, Kyung MinJung, Yong WooLim, Myung Ho
Issue Date
9월-2014
Publisher
KOREAN ACAD MEDICAL SCIENCES
Keywords
Paraphilias; Mental Retardation; Leuprorelin
Citation
JOURNAL OF KOREAN MEDICAL SCIENCE, v.29, no.9, pp.1320 - 1324
Indexed
SCIE
SCOPUS
KCI
Journal Title
JOURNAL OF KOREAN MEDICAL SCIENCE
Volume
29
Number
9
Start Page
1320
End Page
1324
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/97577
DOI
10.3346/jkms.2014.29.9.1320
ISSN
1011-8934
Abstract
Paraphilia is a psychiatric disease that has been difficult to cure. However, recently developed therapeutic methods hold promise. The patient was a 20-yr-old male with chief complaints of continuous masturbation, genital exposure, and aggressive behavior that started 2 yr ago. We administered leuprorelin 3.6 mg intramuscular injection per month, a depot gonadotrophin-releasing hormone analogue, to this patient who a severe mentally retardation with paraphilia. The clinical global impression (CGI)-severity, CGI-improvement and aberrant behavior checklist were performed. After one month, we observed significant improvement in symptoms, such as decreases of abnormal sexual behavior and sexual desire. The GnRH analogues are suggested to be used as an alternative or supplementary therapeutic method for sexual offenders after clinical studies.
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