Recanalization Therapy for Internal Carotid Artery Occlusion Presenting as Acute Ischemic Stroke
DC Field | Value | Language |
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dc.contributor.author | Hong, Jeong-Ho | - |
dc.contributor.author | Kang, Jihoon | - |
dc.contributor.author | Jang, Min Uk | - |
dc.contributor.author | Kim, Beom Joon | - |
dc.contributor.author | Han, Moon-Ku | - |
dc.contributor.author | Park, Tai Hwan | - |
dc.contributor.author | Park, Sang-Soon | - |
dc.contributor.author | Lee, Kyung Bok | - |
dc.contributor.author | Lee, Byung-Chul | - |
dc.contributor.author | Yu, Kyung-Ho | - |
dc.contributor.author | Oh, Mi Sun | - |
dc.contributor.author | Cha, Jae Kwan | - |
dc.contributor.author | Kim, Dae-Hyun | - |
dc.contributor.author | Lee, Jun | - |
dc.contributor.author | Lee, Soo Joo | - |
dc.contributor.author | Ko, Youngchai | - |
dc.contributor.author | Park, Jong-Moo | - |
dc.contributor.author | Kang, Kyusik | - |
dc.contributor.author | Cho, Yong-Jin | - |
dc.contributor.author | Hong, Keun-Sik | - |
dc.contributor.author | Cho, Ki-Hyun | - |
dc.contributor.author | Kim, Joon-Tae | - |
dc.contributor.author | Lee, Juneyoung | - |
dc.contributor.author | Lee, Ji Sung | - |
dc.contributor.author | Bae, Hee-Joon | - |
dc.date.accessioned | 2021-09-05T06:00:02Z | - |
dc.date.available | 2021-09-05T06:00:02Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2014-09 | - |
dc.identifier.issn | 1052-3057 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/97623 | - |
dc.description.abstract | Background: We aimed to describe the current status and clinical outcomes of recanalization therapy for internal carotid artery occlusion (ICAO) presenting as acute ischemic stroke. Methods: Using a nationwide stroke registry database in Korea, we identified consecutive ischemic stroke patients with ICAO hospitalized within 12 hours of onset between March 2010 and November 2011. Results: ICAO accounted for 10.6% (322 of 3028) of acute ischemic strokes within 12 hours of onset. Among the 322 ICAO patients, 53% underwent recanalization therapy, 41% intravenous thrombolysis (IVT) alone, and 59% endovascular treatment (EVT). Twenty-two percent of those with mild deficits (National Institutes of Health Stroke Scale <4) and 50% of those 80 years of age or more received recanalization therapy. Compared with no treatment, recanalization therapy was not significantly associated with a favorable outcome (3-month modified Rankin scale, 0-2) (adjusted odds ratio [OR], 1.77; 95% confidence interval [CI], .80-3.91; P = .16). However, compared with IVT, EVT significantly improved the odds of favorable outcome (OR, 2.86; 95% CI, 1.19-6.88; P = .02) without significant increase of symptomatic intracranial hemorrhage (OR, 2.18; 95% CI, .42-11.43; P = .36) and 3-month mortality (OR, .53; 95% CI, .23-1.18; P = .12). Successful recanalization rate (Thrombolysis in Cerebral Infarction >= 2a) by EVT was 76%. Conclusions: In Korea, one tenth of acute ischemic stroke was caused by ICAO, and about 50% were treated by recanalization therapy. EVT was widely used as a recanalization modality (about 60% of cases) despite lack of evidence. However, its effectiveness and safety were acceptable. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.subject | TISSUE-PLASMINOGEN-ACTIVATOR | - |
dc.subject | INTRAARTERIAL THERAPY | - |
dc.subject | INTERVENTIONAL MANAGEMENT | - |
dc.subject | ENDOVASCULAR TREATMENT | - |
dc.subject | CLINICAL-TRIAL | - |
dc.subject | 0.6 MG/KG | - |
dc.subject | THROMBOLYSIS | - |
dc.subject | THROMBECTOMY | - |
dc.subject | EXPERIENCE | - |
dc.subject | ALTEPLASE | - |
dc.title | Recanalization Therapy for Internal Carotid Artery Occlusion Presenting as Acute Ischemic Stroke | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Juneyoung | - |
dc.identifier.doi | 10.1016/j.jstrokecerebrovasdis.2014.04.025 | - |
dc.identifier.scopusid | 2-s2.0-84908127244 | - |
dc.identifier.wosid | 000341484900040 | - |
dc.identifier.bibliographicCitation | JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, v.23, no.8, pp.2183 - 2189 | - |
dc.relation.isPartOf | JOURNAL OF STROKE & CEREBROVASCULAR DISEASES | - |
dc.citation.title | JOURNAL OF STROKE & CEREBROVASCULAR DISEASES | - |
dc.citation.volume | 23 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 2183 | - |
dc.citation.endPage | 2189 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.relation.journalWebOfScienceCategory | Peripheral Vascular Disease | - |
dc.subject.keywordPlus | TISSUE-PLASMINOGEN-ACTIVATOR | - |
dc.subject.keywordPlus | INTRAARTERIAL THERAPY | - |
dc.subject.keywordPlus | INTERVENTIONAL MANAGEMENT | - |
dc.subject.keywordPlus | ENDOVASCULAR TREATMENT | - |
dc.subject.keywordPlus | CLINICAL-TRIAL | - |
dc.subject.keywordPlus | 0.6 MG/KG | - |
dc.subject.keywordPlus | THROMBOLYSIS | - |
dc.subject.keywordPlus | THROMBECTOMY | - |
dc.subject.keywordPlus | EXPERIENCE | - |
dc.subject.keywordPlus | ALTEPLASE | - |
dc.subject.keywordAuthor | Endovascular recanalization | - |
dc.subject.keywordAuthor | thrombolysis | - |
dc.subject.keywordAuthor | carotid artery | - |
dc.subject.keywordAuthor | acute stroke | - |
dc.subject.keywordAuthor | revascularization | - |
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