Micelle-Mediated Extraction of Dibenzocyclooctadiene Lignans from Schisandra chinensis with Analysis by High-Performance Liquid Chromatography
DC Field | Value | Language |
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dc.contributor.author | Lee, Ki Yong | - |
dc.contributor.author | Shin, Yong-Jun | - |
dc.contributor.author | Kim, Dae Hyun | - |
dc.contributor.author | Park, Jin-Ho | - |
dc.contributor.author | Kim, Seung Hyun | - |
dc.contributor.author | Han, Sang Beom | - |
dc.contributor.author | Sung, Sang Hyun | - |
dc.date.accessioned | 2021-09-05T06:31:54Z | - |
dc.date.available | 2021-09-05T06:31:54Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2014-08 | - |
dc.identifier.issn | 0021-9665 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/97852 | - |
dc.description.abstract | Micelle-mediated extraction offers a convenient alternative to conventional extraction systems. A new method based on micellemediated extraction was developed for the separation and determination of dibenzocyclooctadiene lignans from Schisandra chinensis by high-performance liquid chromatography with photodiode array detection. Various experimental conditions using the micelle-mediated method were investigated to evaluate the extraction process. Ethylene glycol monoalkyl ether (Genapol X-080), a non-ionic surfactant oligoethylene glycol monoalkyl ether, was chosen as the extract solvent. The chromatographic separation was accomplished on a Shiseido Capcell Pak C18 analytical column (250 x 4.6mm i.d., 5 mu m particle diameter), detected by ultraviolet absorption at 254 nm. The isocratic elution was achieved with a mobile phase composed of water-acetonitrile-formic acid (70:30:0.1) at a flow rate of 0.6 mL/min. The method was optimized and fully validated against dibenzocyclooctadiene lignans (schizandrin, gomisin A and gomisin N). With 15% Genapol X-080, a liquid to solid ratio of 100:1 (mL/g) and ultrasonic-assisted extraction for 60 min, the extraction percentage of total dibenzocyclooctadiene lignans reached the highest value. The non-ionic surfactant Genapol X-080 solution is an effective alternative for the extraction of bioactive lignans from S. chinensis. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | OXFORD UNIV PRESS INC | - |
dc.subject | CLOUD-POINT EXTRACTION | - |
dc.subject | BIPHENYL CYCLOOCTENE LIGNANS | - |
dc.subject | ANTIOXIDANT ACTIVITY | - |
dc.subject | NONIONIC SURFACTANT | - |
dc.subject | ASSISTED EXTRACTION | - |
dc.subject | BAILL | - |
dc.subject | CELLS | - |
dc.subject | PRECONCENTRATION | - |
dc.subject | NEUROTOXICITY | - |
dc.subject | SPHENANTHERA | - |
dc.title | Micelle-Mediated Extraction of Dibenzocyclooctadiene Lignans from Schisandra chinensis with Analysis by High-Performance Liquid Chromatography | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Ki Yong | - |
dc.identifier.doi | 10.1093/chromsci/bmt088 | - |
dc.identifier.scopusid | 2-s2.0-84904302213 | - |
dc.identifier.wosid | 000342735100024 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CHROMATOGRAPHIC SCIENCE, v.52, no.7, pp.745 - 750 | - |
dc.relation.isPartOf | JOURNAL OF CHROMATOGRAPHIC SCIENCE | - |
dc.citation.title | JOURNAL OF CHROMATOGRAPHIC SCIENCE | - |
dc.citation.volume | 52 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 745 | - |
dc.citation.endPage | 750 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Biochemical Research Methods | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.subject.keywordPlus | CLOUD-POINT EXTRACTION | - |
dc.subject.keywordPlus | BIPHENYL CYCLOOCTENE LIGNANS | - |
dc.subject.keywordPlus | ANTIOXIDANT ACTIVITY | - |
dc.subject.keywordPlus | NONIONIC SURFACTANT | - |
dc.subject.keywordPlus | ASSISTED EXTRACTION | - |
dc.subject.keywordPlus | BAILL | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordPlus | PRECONCENTRATION | - |
dc.subject.keywordPlus | NEUROTOXICITY | - |
dc.subject.keywordPlus | SPHENANTHERA | - |
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