Creation of hierarchical micro/nano-porous TiO2 surface layer onto Ti implants for improved biocompatibility
DC Field | Value | Language |
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dc.contributor.author | Han, Cheol-Min | - |
dc.contributor.author | Kim, Hyoun-Ee | - |
dc.contributor.author | Koh, Young-Hag | - |
dc.date.accessioned | 2021-09-05T06:48:43Z | - |
dc.date.available | 2021-09-05T06:48:43Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2014-07-25 | - |
dc.identifier.issn | 0257-8972 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/97931 | - |
dc.description.abstract | We created a hierarchical micro/nano-porous TiO2 surface layer onto a Ti substrate to enhance its biocompatibility by mimicking the hierarchical architecture of the native extracellular matrix. To accomplish this, a rough, micro-porous TiO2 layer with pore sizes in the range of 0.5-2 mu m was first formed on the surfaces of a Ti substrate using micro-arc oxidation (MAO) and then coated with a thin layer of pure Ti, similar to 0.5 mu m in thickness, using electron beam (e-beam) evaporation. Subsequently, anodic oxidation was conducted to create a uniform nano-porous TiO2 surface layer with a pore size of similar to 70 nm on the micro-porous layer. This hierarchical micro/nano-porous surface showed considerably enhanced hydrophilicity and in vitro biocompatibility compared to the dense surface and even the micro-porous and nano-porous surfaces. These improvements were attributed to the synergistic effect of micropores and nanopores created by a combination of MAO and anodic oxidation. In addition, protein adsorption capacity was remarkably improved due to the high affinity of the nano-porous TiO2 surface for proteins. (C) 2014 Elsevier B.V. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE SA | - |
dc.subject | TITANIUM IMPLANTS | - |
dc.subject | CELL-ADHESION | - |
dc.subject | OXIDE-FILMS | - |
dc.subject | GROWTH | - |
dc.subject | PROLIFERATION | - |
dc.subject | NANOTUBES | - |
dc.subject | ROUGHNESS | - |
dc.subject | SUBSTRATE | - |
dc.subject | OXIDATION | - |
dc.title | Creation of hierarchical micro/nano-porous TiO2 surface layer onto Ti implants for improved biocompatibility | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Koh, Young-Hag | - |
dc.identifier.doi | 10.1016/j.surfcoat.2014.04.030 | - |
dc.identifier.scopusid | 2-s2.0-84901609804 | - |
dc.identifier.wosid | 000337992100029 | - |
dc.identifier.bibliographicCitation | SURFACE & COATINGS TECHNOLOGY, v.251, pp.226 - 231 | - |
dc.relation.isPartOf | SURFACE & COATINGS TECHNOLOGY | - |
dc.citation.title | SURFACE & COATINGS TECHNOLOGY | - |
dc.citation.volume | 251 | - |
dc.citation.startPage | 226 | - |
dc.citation.endPage | 231 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Coatings & Films | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.subject.keywordPlus | TITANIUM IMPLANTS | - |
dc.subject.keywordPlus | CELL-ADHESION | - |
dc.subject.keywordPlus | OXIDE-FILMS | - |
dc.subject.keywordPlus | GROWTH | - |
dc.subject.keywordPlus | PROLIFERATION | - |
dc.subject.keywordPlus | NANOTUBES | - |
dc.subject.keywordPlus | ROUGHNESS | - |
dc.subject.keywordPlus | SUBSTRATE | - |
dc.subject.keywordPlus | OXIDATION | - |
dc.subject.keywordAuthor | Biocompatibility | - |
dc.subject.keywordAuthor | Porous surface | - |
dc.subject.keywordAuthor | Anodic oxidation | - |
dc.subject.keywordAuthor | E-beam coating | - |
dc.subject.keywordAuthor | Protein delivery | - |
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