Contrast-Enhanced FLAIR (Fluid-Attenuated Inversion Recovery) for Evaluating Mild Traumatic Brain Injury
DC Field | Value | Language |
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dc.contributor.author | Kim, Soo Chin | - |
dc.contributor.author | Park, Sun-Won | - |
dc.contributor.author | Ryoo, Inseon | - |
dc.contributor.author | Jung, Seung Chai | - |
dc.contributor.author | Yun, Tae Jin | - |
dc.contributor.author | Choi, Seung Hong | - |
dc.contributor.author | Kim, Ji-Hoon | - |
dc.contributor.author | Sohn, Chul-Ho | - |
dc.date.accessioned | 2021-09-05T07:03:44Z | - |
dc.date.available | 2021-09-05T07:03:44Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2014-07-16 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/97961 | - |
dc.description.abstract | Purpose: To evaluate whether adding a contrast-enhanced fluid-attenuated inversion recovery (FLAIR) sequence to routine magnetic resonance imaging (MRI) can detect additional abnormalities in the brains of symptomatic patients with mild traumatic brain injury. Materials and Methods: Fifty-four patients with persistent symptoms following mild closed head injury were included in our retrospective study (M:F = 32: 22, mean age: 59.8 +/- 16.4, age range: 26-84 years). All MRI examinations were obtained within 14 days after head trauma (mean: 3.2 +/- 4.1 days, range: 0.2-14 days). Two neuroradiologists recorded (1) the presence of traumatic brain lesions on MR images with and without contrast-enhanced FLAIR images and (2) the pattern and location of meningeal enhancement depicted on contrast-enhanced FLAIR images. The number of additional traumatic brain lesions diagnosed with contrast-enhanced FLAIR was recorded. Correlations between meningeal enhancement and clinical findings were also evaluated. Results: Traumatic brain lesions were detected on routine image sequences in 25 patients. Three additional cases of brain abnormality were detected with the contrast-enhanced FLAIR images. Meningeal enhancement was identified on contrast-enhanced FLAIR images in 9 cases while the other routine image sequences showed no findings of traumatic brain injury. Overall, the additional contrast-enhanced FLAIR images revealed more extensive abnormalities than routine imaging in 37 cases (p<0.001). In multivariate logistic regression analysis, subdural hematoma and posttraumatic loss of consciousness showed a significant association with meningeal enhancement on contrast-enhanced FLAIR images, with odds ratios 13.068 (95% confidence interval 2.037 to 83.852), and 15.487 (95% confidence interval 2.545 to 94.228), respectively. Conclusion: Meningeal enhancement on contrast-enhanced FLAIR images can help detect traumatic brain lesions as well as additional abnormalities not identified on routine unenhanced MRI. Therefore contrast-enhanced FLAIR MR imaging is recommended when a contrast MR study is indicated in a patient with a symptomatic prior closed mild head injury. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | PUBLIC LIBRARY SCIENCE | - |
dc.subject | DIFFUSE AXONAL INJURY | - |
dc.subject | HEAD-INJURY | - |
dc.subject | SUBDURAL-HEMATOMA | - |
dc.subject | MR | - |
dc.subject | MENINGES | - |
dc.subject | SEQUELAE | - |
dc.subject | RESECTION | - |
dc.subject | SPACE | - |
dc.subject | SITE | - |
dc.title | Contrast-Enhanced FLAIR (Fluid-Attenuated Inversion Recovery) for Evaluating Mild Traumatic Brain Injury | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Ryoo, Inseon | - |
dc.identifier.doi | 10.1371/journal.pone.0102229 | - |
dc.identifier.scopusid | 2-s2.0-84904302387 | - |
dc.identifier.wosid | 000341306600049 | - |
dc.identifier.bibliographicCitation | PLOS ONE, v.9, no.7 | - |
dc.relation.isPartOf | PLOS ONE | - |
dc.citation.title | PLOS ONE | - |
dc.citation.volume | 9 | - |
dc.citation.number | 7 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | DIFFUSE AXONAL INJURY | - |
dc.subject.keywordPlus | HEAD-INJURY | - |
dc.subject.keywordPlus | SUBDURAL-HEMATOMA | - |
dc.subject.keywordPlus | MR | - |
dc.subject.keywordPlus | MENINGES | - |
dc.subject.keywordPlus | SEQUELAE | - |
dc.subject.keywordPlus | RESECTION | - |
dc.subject.keywordPlus | SPACE | - |
dc.subject.keywordPlus | SITE | - |
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