Risk Factors Associated with Poor Outcomes in Patients with Brain Abscesses
DC Field | Value | Language |
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dc.contributor.author | Ko, Seok-Jin | - |
dc.contributor.author | Park, Kyung-Jae | - |
dc.contributor.author | Park, Dong-Hyuk | - |
dc.contributor.author | Kang, Shin-Hyuk | - |
dc.contributor.author | Park, Jung-Yul | - |
dc.contributor.author | Chung, Yong-Gu | - |
dc.date.accessioned | 2021-09-05T07:20:07Z | - |
dc.date.available | 2021-09-05T07:20:07Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2014-07 | - |
dc.identifier.issn | 2005-3711 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/98073 | - |
dc.description.abstract | Objective : The purpose of this study was to describe the clinical characteristics, treatment outcomes, and prognostic factors in patients with brain abscesses treated in a single institute during a recent 10-year period. Methods : Fifty-one patients with brain abscesses who underwent navigation-assisted abscess aspiration with antibiotic treatment were included in this study. Variable parameters were collected from the patients' medical records and radiological data. A comparison was made between patients with favorable [Glasgow Outcome Scale (GOS) >= 4] and unfavorable (GOS <4) outcomes at discharge. Additionally, we investigated the factors influencing the duration of antibiotic administration. Results : The study included 41 male and 10 female patients with a mean age of 53 years. At admission, 42 patients (82%) showed either clear or mildly disturbed consciousness (GCS >= 13) and 24 patients (47%) had predisposing factors. The offending microorganisms were identified in 25 patients (49%), and Streptococcus species were the most commonly isolated bacteria (27%). The mean duration of antibiotic administration was 42 days. At discharge, 41 patients had a favorable outcome and 10 had an unfavorable outcome including 8 deaths. The decreased level of consciousness (GCS <13) on admission was likely associated with an unfavorable outcome (p=0.052), and initial hyperglycemia (>= 140 mg/dL) was an independent risk factor for prolonged antibiotic therapy (p=0.032). Conclusion : We found that the level of consciousness at admission was associated with treatment outcomes in patients with brain abscesses. Furthermore, initial hyperglycemia was closely related to the long-term use of antibiotic agents. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN NEUROSURGICAL SOC | - |
dc.subject | INTENSIVE INSULIN THERAPY | - |
dc.subject | HYPERGLYCEMIA | - |
dc.subject | MORTALITY | - |
dc.subject | ISCHEMIA | - |
dc.subject | TRENDS | - |
dc.title | Risk Factors Associated with Poor Outcomes in Patients with Brain Abscesses | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, Kyung-Jae | - |
dc.contributor.affiliatedAuthor | Park, Dong-Hyuk | - |
dc.contributor.affiliatedAuthor | Kang, Shin-Hyuk | - |
dc.contributor.affiliatedAuthor | Park, Jung-Yul | - |
dc.contributor.affiliatedAuthor | Chung, Yong-Gu | - |
dc.identifier.doi | 10.3340/jkns.2014.56.1.34 | - |
dc.identifier.scopusid | 2-s2.0-84929921024 | - |
dc.identifier.wosid | 000342333500007 | - |
dc.identifier.bibliographicCitation | JOURNAL OF KOREAN NEUROSURGICAL SOCIETY, v.56, no.1, pp.34 - 41 | - |
dc.relation.isPartOf | JOURNAL OF KOREAN NEUROSURGICAL SOCIETY | - |
dc.citation.title | JOURNAL OF KOREAN NEUROSURGICAL SOCIETY | - |
dc.citation.volume | 56 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 34 | - |
dc.citation.endPage | 41 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002089758 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.subject.keywordPlus | INTENSIVE INSULIN THERAPY | - |
dc.subject.keywordPlus | HYPERGLYCEMIA | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | ISCHEMIA | - |
dc.subject.keywordPlus | TRENDS | - |
dc.subject.keywordAuthor | Brain abscess | - |
dc.subject.keywordAuthor | Glasgow Coma Scale | - |
dc.subject.keywordAuthor | Glasgow Outcome Scale | - |
dc.subject.keywordAuthor | Hyperglycemia | - |
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