Radiotherapy-induced secondary cancer risk for breast cancer: 3D conformal therapy versus IMRT versus VMAT
DC Field | Value | Language |
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dc.contributor.author | Lee, Boram | - |
dc.contributor.author | Lee, Sunyoung | - |
dc.contributor.author | Sung, Jiwon | - |
dc.contributor.author | Yoon, Myonggeun | - |
dc.date.accessioned | 2021-09-05T08:15:30Z | - |
dc.date.available | 2021-09-05T08:15:30Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2014-06 | - |
dc.identifier.issn | 0952-4746 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/98317 | - |
dc.description.abstract | This study evaluated the secondary cancer risk to various organs due to radiation treatment for breast cancer. Organ doses to an anthropomorphic phantom were measured using a photoluminescent dosimeter (PLD) for breast cancer treatment with 3D conformal radiation therapy (3D-CRT), intensity modulated radiation therapy (IMRT), and volumetric modulated arc therapy (VMAT). Cancer risk based on the measured dose was calculated using the BEIR (Biological Effects of Ionizing Radiation) VII models. The secondary dose per treatment dose (50.4 Gy) to various organs ranged from 0.02 to 0.36 Gy for 3D-CRT, but from 0.07 to 8.48 Gy for IMRT and VMAT, indicating that the latter methods are associated with higher secondary radiation doses than 3D-CRT. The result of the homogeneity index in the breast target shows that the dose homogeneity of 3D-CRT was worse than those of IMRT and VMAT. The organ specific lifetime attributable risks (LARs) to the thyroid, contralateral breast and ipsilateral lung per 100 000 population were 0.02, 19.71, and 0.76 respectively for 3D-CRT, much lower than the 0.11, 463.56, and 10.59 respectively for IMRT and the 0.12, 290.32, and 12.28 respectively for VMAT. The overall estimation of LAR indicated that the radiation-induced cancer risk due to breast radiation therapy was lower with 3D-CRT than with IMRT or VMAT. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | IOP PUBLISHING LTD | - |
dc.subject | MODULATED RADIATION-THERAPY | - |
dc.subject | FIELD-IN-FIELD | - |
dc.subject | 2ND CANCER | - |
dc.subject | CONVENTIONAL WEDGE | - |
dc.subject | IPSILATERAL LUNG | - |
dc.subject | ARC THERAPY | - |
dc.subject | PROTON | - |
dc.subject | IRRADIATION | - |
dc.subject | PHOTON | - |
dc.subject | STANDARD | - |
dc.title | Radiotherapy-induced secondary cancer risk for breast cancer: 3D conformal therapy versus IMRT versus VMAT | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Yoon, Myonggeun | - |
dc.identifier.doi | 10.1088/0952-4746/34/2/325 | - |
dc.identifier.scopusid | 2-s2.0-84902074471 | - |
dc.identifier.wosid | 000337904600012 | - |
dc.identifier.bibliographicCitation | JOURNAL OF RADIOLOGICAL PROTECTION, v.34, no.2, pp.325 - 331 | - |
dc.relation.isPartOf | JOURNAL OF RADIOLOGICAL PROTECTION | - |
dc.citation.title | JOURNAL OF RADIOLOGICAL PROTECTION | - |
dc.citation.volume | 34 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 325 | - |
dc.citation.endPage | 331 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Environmental Sciences & Ecology | - |
dc.relation.journalResearchArea | Public, Environmental & Occupational Health | - |
dc.relation.journalResearchArea | Nuclear Science & Technology | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Environmental Sciences | - |
dc.relation.journalWebOfScienceCategory | Public, Environmental & Occupational Health | - |
dc.relation.journalWebOfScienceCategory | Nuclear Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | MODULATED RADIATION-THERAPY | - |
dc.subject.keywordPlus | FIELD-IN-FIELD | - |
dc.subject.keywordPlus | 2ND CANCER | - |
dc.subject.keywordPlus | CONVENTIONAL WEDGE | - |
dc.subject.keywordPlus | IPSILATERAL LUNG | - |
dc.subject.keywordPlus | ARC THERAPY | - |
dc.subject.keywordPlus | PROTON | - |
dc.subject.keywordPlus | IRRADIATION | - |
dc.subject.keywordPlus | PHOTON | - |
dc.subject.keywordPlus | STANDARD | - |
dc.subject.keywordAuthor | secondary cancer risk | - |
dc.subject.keywordAuthor | breast cancer | - |
dc.subject.keywordAuthor | BEIR VII | - |
dc.subject.keywordAuthor | lifetime attributable risk | - |
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