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Salmonella typhimurium with gamma-radiation induced H(2)AX phosphorylation and apoptosis in melanoma

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dc.contributor.authorYoon, Won Suck-
dc.contributor.authorKim, Sinyeon-
dc.contributor.authorSeo, Sungchul-
dc.contributor.authorPark, Yongkeun-
dc.date.accessioned2021-09-05T08:19:07Z-
dc.date.available2021-09-05T08:19:07Z-
dc.date.created2021-06-15-
dc.date.issued2014-06-
dc.identifier.issn0916-8451-
dc.identifier.urihttps://scholar.korea.ac.kr/handle/2021.sw.korea/98340-
dc.description.abstractTo investigate the combinatorial effects using Salmonella and gamma-radiation, the Salmonella typhimurium infection in combination with gamma-radiation was investigated on melanoma. We showed that ROS expression and H(2)AX phosphorylation increased during stress by gamma-radiation irrespective of Salmonella infection, inducing apoptosis by caspase-3 and bcl2 in tumor cells. In addition, tumor growth was suppressed by this combinatory therapy suggesting candidates for radiation therapy against melanoma.-
dc.languageEnglish-
dc.language.isoen-
dc.publisherTAYLOR & FRANCIS LTD-
dc.subjectIN-VIVO-
dc.subjectTHERAPY-
dc.subjectCANCER-
dc.subjectMUTANT-
dc.subjectVECTOR-
dc.titleSalmonella typhimurium with gamma-radiation induced H(2)AX phosphorylation and apoptosis in melanoma-
dc.typeArticle-
dc.contributor.affiliatedAuthorYoon, Won Suck-
dc.contributor.affiliatedAuthorSeo, Sungchul-
dc.identifier.doi10.1080/09168451.2014.905173-
dc.identifier.scopusid2-s2.0-84925855407-
dc.identifier.wosid000340133800026-
dc.identifier.bibliographicCitationBIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, v.78, no.6, pp.1082 - 1085-
dc.relation.isPartOfBIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY-
dc.citation.titleBIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY-
dc.citation.volume78-
dc.citation.number6-
dc.citation.startPage1082-
dc.citation.endPage1085-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaBiochemistry & Molecular Biology-
dc.relation.journalResearchAreaBiotechnology & Applied Microbiology-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalResearchAreaFood Science & Technology-
dc.relation.journalWebOfScienceCategoryBiochemistry & Molecular Biology-
dc.relation.journalWebOfScienceCategoryBiotechnology & Applied Microbiology-
dc.relation.journalWebOfScienceCategoryChemistry, Applied-
dc.relation.journalWebOfScienceCategoryFood Science & Technology-
dc.subject.keywordPlusIN-VIVO-
dc.subject.keywordPlusTHERAPY-
dc.subject.keywordPlusCANCER-
dc.subject.keywordPlusMUTANT-
dc.subject.keywordPlusVECTOR-
dc.subject.keywordAuthorH2A histone family member (H(2)AX)-
dc.subject.keywordAuthormelanoma-
dc.subject.keywordAuthorradiotherapy-
dc.subject.keywordAuthorreactive oxygen species (ROS)-
dc.subject.keywordAuthorSalmonella typhimurium-
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