Vascular endothelial growth factor gene polymorphisms and vasculitis susceptibility: A meta-analysis
DC Field | Value | Language |
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dc.contributor.author | Song, Gwan Gyu | - |
dc.contributor.author | Kim, Jae-Hoon | - |
dc.contributor.author | Lee, Young Ho | - |
dc.date.accessioned | 2021-09-05T08:27:55Z | - |
dc.date.available | 2021-09-05T08:27:55Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2014-06 | - |
dc.identifier.issn | 0198-8859 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/98399 | - |
dc.description.abstract | Objective: The aim of this study was to explore whether vascular endothelial growth factor (VEGF) polymorphisms are associated with susceptibility to vasculitis. Methods: Meta-analyses were conducted on the associations between the -634 C/G, +936 C/T, -1154 A/ G, and -2578 A/C polymorphisms of VEGF and vasculitis. Results: Eight studies on VEGF polymorphisms and vasculitis involving 2740 subjects (vasculitis 834, controls 1906) were included in this meta-analysis. The meta-analysis showed no association between vasculitis and the VEGF 634 C allele (OR=1.161, 95% Cl=0.921-1.464, p=0.207) among study subjects. Meta-analysis showed no association between vasculitis and the VEGF + 936 T allele (OR=1.121, 95% CI=0.905-1.390, p=0.295). However, stratification by ethnicity indicated a significant association between the VEGF + 936 T allele and vasculitis in Europeans, but not in Asians (OR=1.486, 95% CI=1.038-2.128, p=0.030; OR=0.958, 95% CI=0.773-1.253, p=0.755). Meta-analysis showed no association between vasculitis and the VEGF -1154 A/G and 2578 A/C polymorphisms. Conclusions: This meta-analysis suggests that the VEGF + 936 T allele is associated with susceptibility to vasculitis in Europeans, but not in Asians. (C) 2014 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.subject | KAWASAKI-DISEASE | - |
dc.subject | FACTOR VEGF | - |
dc.subject | ASSOCIATION | - |
dc.subject | COMPLICATIONS | - |
dc.subject | HAPLOTYPES | - |
dc.title | Vascular endothelial growth factor gene polymorphisms and vasculitis susceptibility: A meta-analysis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Song, Gwan Gyu | - |
dc.contributor.affiliatedAuthor | Lee, Young Ho | - |
dc.identifier.doi | 10.1016/j.humimm.2014.02.022 | - |
dc.identifier.scopusid | 2-s2.0-84900474910 | - |
dc.identifier.wosid | 000336465100008 | - |
dc.identifier.bibliographicCitation | HUMAN IMMUNOLOGY, v.75, no.6, pp.541 - 548 | - |
dc.relation.isPartOf | HUMAN IMMUNOLOGY | - |
dc.citation.title | HUMAN IMMUNOLOGY | - |
dc.citation.volume | 75 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 541 | - |
dc.citation.endPage | 548 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.subject.keywordPlus | KAWASAKI-DISEASE | - |
dc.subject.keywordPlus | FACTOR VEGF | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | COMPLICATIONS | - |
dc.subject.keywordPlus | HAPLOTYPES | - |
dc.subject.keywordAuthor | Vasculitis | - |
dc.subject.keywordAuthor | VEGF | - |
dc.subject.keywordAuthor | Polymorphism | - |
dc.subject.keywordAuthor | Meta-analysis | - |
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