Efficiency of genomic DNA extraction dependent on the size of magnetic nanoclusters
- Authors
- Cho, Hyun Ah; Min, Ji Hyun; Wu, Jun Hua; Jang, Jin Woo; Lim, Chae-Seung; Kim, Young Keun
- Issue Date
- 7-5월-2014
- Publisher
- AMER INST PHYSICS
- Citation
- JOURNAL OF APPLIED PHYSICS, v.115, no.17
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF APPLIED PHYSICS
- Volume
- 115
- Number
- 17
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/98529
- DOI
- 10.1063/1.4864736
- ISSN
- 0021-8979
- Abstract
- We report the efficiency of genomic DNA extraction as a function of particle size and quantity. For DNA extraction, we synthesized magnetic nanoclusters of various sizes and coated the surface of these magnetic nanoclusters with meso-2,3-dimercaptosuccinic acid. We showed that the nanoclusters had a tight particle size distribution and high crystallinity. Furthermore, we observed that the three types of magnetic nanoclusters studied exhibited ferrimagnetic behavior and that larger nanoclusters showed larger saturation magnetization values. The resultant efficiency of DNA extraction is inversely proportional to particle size in the range of nanoclusters tested, due to the fact that the surface-to-volume ratio decreases as particle size increases. (C) 2014 AIP Publishing LLC.
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Collections - Graduate School > Department of Biomedical Sciences > 1. Journal Articles
- College of Engineering > Department of Materials Science and Engineering > 1. Journal Articles
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