Facilely fabricating PCL nanofibrous scaffolds with hierarchical pore structure for tissue engineering
DC Field | Value | Language |
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dc.contributor.author | Du, Yuzhang | - |
dc.contributor.author | Chen, Xiaofeng | - |
dc.contributor.author | Koh, Young Hag | - |
dc.contributor.author | Lei, Bo | - |
dc.date.accessioned | 2021-09-05T08:58:17Z | - |
dc.date.available | 2021-09-05T08:58:17Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2014-05-01 | - |
dc.identifier.issn | 0167-577X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/98552 | - |
dc.description.abstract | Highly hierarchical pore structure (macro-micro-nano) for biomimetic nanofibrous scaffolds could efficiently enhance cell infiltration and tissue formation. However, it is difficult to prepare these structures by using traditional electrostatic spinning techniques. Here, we report a facile method to fabricate polycaprolactone (PCL) nanofibrous scaffolds with multi-scale pore structure by simple phase separation. By employing water-dioxane as solvents and tris spheres as macropore template, PCL nanofibrous scaffolds with pores 300-800 mu m, 1-10 mu m and 100-1000 nm in diameter can be facilely produced. All scaffolds possess controlled nanofibrous morphology and porosity (90-98%). This scaffold may provide promising applications in tissue engineering and drug delivery. (c) 2014 Elsevier B.V. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.subject | PHASE-SEPARATION | - |
dc.subject | BONE | - |
dc.subject | POLYCAPROLACTONE | - |
dc.title | Facilely fabricating PCL nanofibrous scaffolds with hierarchical pore structure for tissue engineering | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Koh, Young Hag | - |
dc.identifier.doi | 10.1016/j.matlet.2014.02.031 | - |
dc.identifier.scopusid | 2-s2.0-84894683292 | - |
dc.identifier.wosid | 000335109500017 | - |
dc.identifier.bibliographicCitation | MATERIALS LETTERS, v.122, pp.62 - 65 | - |
dc.relation.isPartOf | MATERIALS LETTERS | - |
dc.citation.title | MATERIALS LETTERS | - |
dc.citation.volume | 122 | - |
dc.citation.startPage | 62 | - |
dc.citation.endPage | 65 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.subject.keywordPlus | PHASE-SEPARATION | - |
dc.subject.keywordPlus | BONE | - |
dc.subject.keywordPlus | POLYCAPROLACTONE | - |
dc.subject.keywordAuthor | Biomaterials | - |
dc.subject.keywordAuthor | Porous materials | - |
dc.subject.keywordAuthor | Nanofibrous scaffolds | - |
dc.subject.keywordAuthor | Phase separation | - |
dc.subject.keywordAuthor | Hierarchical pores | - |
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