Shape-Memory Effect by Specific Biodegradable Polymer Blending for Biomedical Applications
- Authors
- Cha, Kook Jin; Lih, Eugene; Choi, Jiyeon; Joung, Yoon Ki; Ahn, Dong Jun; Han, Dong Keun
- Issue Date
- 5월-2014
- Publisher
- WILEY-V C H VERLAG GMBH
- Keywords
- biodegradable polymers; biomedical applications; glass transition temperature; polymer blends; shape memory polymers
- Citation
- MACROMOLECULAR BIOSCIENCE, v.14, no.5, pp.667 - 678
- Indexed
- SCIE
SCOPUS
- Journal Title
- MACROMOLECULAR BIOSCIENCE
- Volume
- 14
- Number
- 5
- Start Page
- 667
- End Page
- 678
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/98613
- DOI
- 10.1002/mabi.201300481
- ISSN
- 1616-5187
- Abstract
- Specific biodegradable polymers having shape-memory properties through "polymer-blend'' method are investigated and their shape-switching in body temperature (37 degrees C) is characterized. Poly(L-lactide-co-caprolactone) (PLCL) and poly(L-lactide-co-glycolide) (PLGA) are dissolved in chloroform and the films of several blending ratios of PLCL/PLGA are prepared by solvent casting. The shape-memory properties of films are also examined using dynamic mechanical analysis (DMA). Among the blending ratios, the PLCL50/PLGA50 film shows good performance of shape-fixity and shape-recovery based on glass transition temperature. It displays that the degree of shape recovery is 100% at 37 degrees C and the shape recovery proceeds within only 15 s. In vitro biocompatibility studies are shown to have good blood compatibility and cytocompatibility for the PLCL50/PLGA50 films. It is expected that this blended biodegradable polymer can be potentially used as a material for blood-contacting medical devices such as a self-expended vascular polymer stents and vascular closure devices in biomedical applications.
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Collections - College of Engineering > Department of Chemical and Biological Engineering > 1. Journal Articles
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