Non-HDL cholesterol is an independent risk factor for aspirin resistance in obese patients with type 2 diabetes
DC Field | Value | Language |
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dc.contributor.author | Kim, Jong Dai | - |
dc.contributor.author | Park, Cheol-Young | - |
dc.contributor.author | Ahn, Kue Jeong | - |
dc.contributor.author | Cho, Jae Hyoung | - |
dc.contributor.author | Choi, Kyung Mook | - |
dc.contributor.author | Kang, Jun Goo | - |
dc.contributor.author | Kim, Jae Hyeon | - |
dc.contributor.author | Lee, Ki Young | - |
dc.contributor.author | Lee, Byung Wan | - |
dc.contributor.author | Mok, Ji Oh | - |
dc.contributor.author | Moon, Min Kyong | - |
dc.contributor.author | Park, Joong Yeol | - |
dc.contributor.author | Park, Sung Woo | - |
dc.date.accessioned | 2021-09-05T09:09:01Z | - |
dc.date.available | 2021-09-05T09:09:01Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2014-05 | - |
dc.identifier.issn | 0021-9150 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/98627 | - |
dc.description.abstract | Objective: We evaluated the prevalence of aspirin resistance and predictive factors for aspirin resistance in Korean type 2 diabetes patients. Approach and results: A total of 1045 type 2 diabetes patients from 11 hospitals who were taking aspirin (100 mg/day for >= 2 weeks) and no other antiplatelet agents were studied to evaluate aspirin resistance. Aspirin resistance was measured in aspirin reaction units using VerifyNow (R). Aspirin resistance was defined as >= 550 aspirin reaction units. Aspirin resistance was detected in 102 of the 1045 subjects (prevalence 9.8%). Aspirin resistance was associated with total cholesterol (P = 0.013), LDL-cholesterol (P = 0.028), and non-HDL cholesterol (P = 0.008) concentrations in univariate analysis. In multivariate logistic regression analysis, only non-HDL cholesterol was associated with aspirin resistance in obese (BMI > 25 kg/m(2)) type 2 diabetes patients (adjusted odds ratio 3.55, 95% CI: 1.25-10.05, P = 0.017). Conclusions: The prevalence of aspirin resistance in Korean type 2 diabetes patients is 9.8%. Non-HDL cholesterol is an independent risk factor for aspirin resistance, especially in obese type 2 diabetes patients. (C) 2014 Elsevier Ireland Ltd. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER IRELAND LTD | - |
dc.subject | CORONARY-ARTERY-DISEASE | - |
dc.subject | LOW-DENSITY-LIPOPROTEIN | - |
dc.subject | PLATELET-FUNCTION | - |
dc.subject | PREVALENCE | - |
dc.subject | AGGREGATION | - |
dc.subject | CLOPIDOGREL | - |
dc.subject | REACTIVITY | - |
dc.subject | MORTALITY | - |
dc.subject | EVENTS | - |
dc.title | Non-HDL cholesterol is an independent risk factor for aspirin resistance in obese patients with type 2 diabetes | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Choi, Kyung Mook | - |
dc.identifier.doi | 10.1016/j.atherosclerosis.2014.01.015 | - |
dc.identifier.scopusid | 2-s2.0-84897939773 | - |
dc.identifier.wosid | 000334337300024 | - |
dc.identifier.bibliographicCitation | ATHEROSCLEROSIS, v.234, no.1, pp.146 - 151 | - |
dc.relation.isPartOf | ATHEROSCLEROSIS | - |
dc.citation.title | ATHEROSCLEROSIS | - |
dc.citation.volume | 234 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 146 | - |
dc.citation.endPage | 151 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.relation.journalWebOfScienceCategory | Peripheral Vascular Disease | - |
dc.subject.keywordPlus | CORONARY-ARTERY-DISEASE | - |
dc.subject.keywordPlus | LOW-DENSITY-LIPOPROTEIN | - |
dc.subject.keywordPlus | PLATELET-FUNCTION | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | AGGREGATION | - |
dc.subject.keywordPlus | CLOPIDOGREL | - |
dc.subject.keywordPlus | REACTIVITY | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | EVENTS | - |
dc.subject.keywordAuthor | Aspirin resistance | - |
dc.subject.keywordAuthor | Non-HDL cholesterol | - |
dc.subject.keywordAuthor | Atherogenic dyslipidemia | - |
dc.subject.keywordAuthor | Diabetes | - |
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