Complete phenotypic and metabolic profiles of a large consecutive cohort of untreated Korean women with polycystic ovary syndrome
DC Field | Value | Language |
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dc.contributor.author | Kim, Jin Ju | - |
dc.contributor.author | Hwang, Kyu Ri | - |
dc.contributor.author | Choi, Young Min | - |
dc.contributor.author | Moon, Shin Yong | - |
dc.contributor.author | Chae, Soo Jin | - |
dc.contributor.author | Park, Chan Woo | - |
dc.contributor.author | Kim, Hye Ok | - |
dc.contributor.author | Choi, Doo Seok | - |
dc.contributor.author | Kwon, Hyuck Chan | - |
dc.contributor.author | Kang, Byung Moon | - |
dc.contributor.author | Lee, Byung Seok | - |
dc.contributor.author | Cho, Si Hyun | - |
dc.contributor.author | Kim, Tai June | - |
dc.contributor.author | Kim, Tak | - |
dc.contributor.author | Kim, Min Ju | - |
dc.contributor.author | Park, Hyun Young | - |
dc.date.accessioned | 2021-09-05T09:13:25Z | - |
dc.date.available | 2021-09-05T09:13:25Z | - |
dc.date.created | 2021-06-15 | - |
dc.date.issued | 2014-05 | - |
dc.identifier.issn | 0015-0282 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/98654 | - |
dc.description.abstract | Objective: To investigate the complete metabolic and phenotypic profiles of a large cohort of untreated, consecutively recruited Korean women with polycystic ovary syndrome (PCOS), for whom a registry for Korean women with PCOS was constructed. Design: Observational study. Setting: Three infertility clinics and 10 university hospitals. Patient(s): Eight hundred sixty-five women with PCOS were recruited using the Rotterdam criteria. Intervention(s): Standardized evaluation protocol and web-based case report form. Main Outcome Measure(s): Metabolic and phenotypic profiles. Result(s): The subjects with PCOS mainly consisted of young and nonobese women. The most problematic subjective symptom was menstrual disturbance or infertility, and, on average, the patients seemed to menstruate every 2 months. PCO morphology was observed in 96.5% of the patients. Although few women visited hospitals owing to HA symptoms alone, hirsutism was observed in one-third of the patients (33.9%) and half (47.4%) of the patients had biochemical HA. About one-fifth (20.1%) of the patients had generalized obesity, and one-third (33.2%) had central obesity. Prevalence of dyslipidemia, diabetes, hypertension, and metabolic syndrome were 35.7%, 3.5%, 4.0%, and 13.7%, respectively. Prevalence of prediabetes was 20.8%, and a substantial proportion of additional subjects with normal fasting plasma glucose or oral glucose tolerance tests were identified as having prediabetes by hemoglobin A1(C) testing. Conclusion(s): Our well-defined cohort provided comprehensive estimates of the features of metabolic and phenotypic profiles related to PCOS in Korean women. Further longitudinal follow-up studies are needed to investigate the changes in phenotypic and metabolic markers in this PCOS cohort. (C) 2014 by American Society for Reproductive Medicine. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.subject | SYNDROME PCOS | - |
dc.subject | CHINESE WOMEN | - |
dc.subject | PREVALENCE | - |
dc.subject | CONSENSUS | - |
dc.subject | DIAGNOSIS | - |
dc.subject | CRITERIA | - |
dc.subject | SAMPLE | - |
dc.title | Complete phenotypic and metabolic profiles of a large consecutive cohort of untreated Korean women with polycystic ovary syndrome | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Tak | - |
dc.identifier.doi | 10.1016/j.fertnstert.2014.01.049 | - |
dc.identifier.scopusid | 2-s2.0-84899988873 | - |
dc.identifier.wosid | 000335504600047 | - |
dc.identifier.bibliographicCitation | FERTILITY AND STERILITY, v.101, no.5, pp.1424 - U54 | - |
dc.relation.isPartOf | FERTILITY AND STERILITY | - |
dc.citation.title | FERTILITY AND STERILITY | - |
dc.citation.volume | 101 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 1424 | - |
dc.citation.endPage | U54 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Obstetrics & Gynecology | - |
dc.relation.journalResearchArea | Reproductive Biology | - |
dc.relation.journalWebOfScienceCategory | Obstetrics & Gynecology | - |
dc.relation.journalWebOfScienceCategory | Reproductive Biology | - |
dc.subject.keywordPlus | SYNDROME PCOS | - |
dc.subject.keywordPlus | CHINESE WOMEN | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | CONSENSUS | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | CRITERIA | - |
dc.subject.keywordPlus | SAMPLE | - |
dc.subject.keywordAuthor | Metabolic syndrome | - |
dc.subject.keywordAuthor | phenotype | - |
dc.subject.keywordAuthor | polycystic ovary syndrome | - |
dc.subject.keywordAuthor | Rotterdam criteria | - |
dc.subject.keywordAuthor | type 2 diabetes | - |
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