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Experiences on Conversion to Once-Daily Advagraf and Sirolimus Combination in Stable Kidney Recipients

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dc.contributor.authorJun, H.-
dc.contributor.authorJung, C. -W.-
dc.contributor.authorKim, M. -G.-
dc.contributor.authorPark, K. -T.-
dc.date.accessioned2021-09-05T10:58:45Z-
dc.date.available2021-09-05T10:58:45Z-
dc.date.created2021-06-15-
dc.date.issued2014-03-
dc.identifier.issn0041-1345-
dc.identifier.urihttps://scholar.korea.ac.kr/handle/2021.sw.korea/99128-
dc.description.abstractIn transplant recipients, nephrotoxicity due to long-term use of calcineurin inhibitor (CM) is a serious problem that cannot be overlooked. Medication compliance can cause graft failure in transplant recipients who are bound to long-term medication. In this study, 36 patients who underwent conversion to once-daily Advagraft and sirolimus combination at Korea University Anam Hospital from September 2011 to March 2013 were retrospectively reviewed at 3 and 6 months for laboratory findings, mean arterial pressure (MAP), and so on. After conversion, serum creatinine level and glomerular filtration rate (GFR) decreased significantly at 3 months (P = .024 and P < .001, respectively). Fasting serum glucose level and proteinuria increased significantly at 6 months (P = .016 and P = .030, respectively). The impact of time after conversion at 3 months was significantly related to the increase in postoperative estimated glomerular filtration rate (eGFR). Graft rejection, morbidity, and mortality did not occur within the study period. A once-daily Advagraf and sirolimus regimen can be a novel standard regimen in stable kidney recipients due to its effects in improving renal function and convenience for patients.-
dc.languageEnglish-
dc.language.isoen-
dc.publisherELSEVIER SCIENCE INC-
dc.subjectLIVER-TRANSPLANT RECIPIENTS-
dc.subjectRENAL-TRANSPLANTATION-
dc.subjectADHERENCE-
dc.subjectSURVIVAL-
dc.subjectEXPOSURE-
dc.subjectSAFETY-
dc.subjectTRIAL-
dc.subjectGRAFT-
dc.titleExperiences on Conversion to Once-Daily Advagraf and Sirolimus Combination in Stable Kidney Recipients-
dc.typeArticle-
dc.contributor.affiliatedAuthorJung, C. -W.-
dc.contributor.affiliatedAuthorKim, M. -G.-
dc.identifier.doi10.1016/j.transproceed.2014.01.004-
dc.identifier.wosid000333572100025-
dc.identifier.bibliographicCitationTRANSPLANTATION PROCEEDINGS, v.46, no.2, pp.400 - 402-
dc.relation.isPartOfTRANSPLANTATION PROCEEDINGS-
dc.citation.titleTRANSPLANTATION PROCEEDINGS-
dc.citation.volume46-
dc.citation.number2-
dc.citation.startPage400-
dc.citation.endPage402-
dc.type.rimsART-
dc.type.docTypeArticle; Proceedings Paper-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaImmunology-
dc.relation.journalResearchAreaSurgery-
dc.relation.journalResearchAreaTransplantation-
dc.relation.journalWebOfScienceCategoryImmunology-
dc.relation.journalWebOfScienceCategorySurgery-
dc.relation.journalWebOfScienceCategoryTransplantation-
dc.subject.keywordPlusLIVER-TRANSPLANT RECIPIENTS-
dc.subject.keywordPlusRENAL-TRANSPLANTATION-
dc.subject.keywordPlusADHERENCE-
dc.subject.keywordPlusSURVIVAL-
dc.subject.keywordPlusEXPOSURE-
dc.subject.keywordPlusSAFETY-
dc.subject.keywordPlusTRIAL-
dc.subject.keywordPlusGRAFT-
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