Quantitative characterization for dielectrophoretic behavior of biological cells using optical tweezers
- Authors
- Park, In Soo; Park, Se Hee; Lee, Sang Woo; Yoon, Dae Sung; Kim, Beop-Min
- Issue Date
- 3-2월-2014
- Publisher
- AMER INST PHYSICS
- Citation
- APPLIED PHYSICS LETTERS, v.104, no.5
- Indexed
- SCIE
SCOPUS
- Journal Title
- APPLIED PHYSICS LETTERS
- Volume
- 104
- Number
- 5
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/99308
- DOI
- 10.1063/1.4862746
- ISSN
- 0003-6951
- Abstract
- We report a method to precisely quantify dielectrophoretic (DEP) forces and cutoff frequencies (f(c)) of viable and nonviable yeast cells. The method consists of a two-step process in which generated DEP forces act upon a cell through a micro-electrode device, followed by direct measurement of DEP forces using optical tweezers. DEP behaviors of viable and nonviable yeast cells are monitored as a function of AC frequency. We believe that the proposed method can be used as a powerful platform for cell-based assays to characterize the DEP behavior of various cell types including cancer and normal cells. (C) 2014 AIP Publishing LLC.
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Collections - Graduate School > Department of Bioengineering > 1. Journal Articles
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