Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Prognosis after Implantation of Cardioverter-Defibrillators in Korean Patients with Brugada Syndrome

Authors
Son, Myoung KyunByeon, KyeongminPark, Seung-JungKim, June SooNam, Gi-ByoungChoi, Kee-JoonKim, You-HoPark, Sang WeonKim, Young-HoonPark, Hyung WookCho, Jeong GwanOn, Young Keun
Issue Date
1-1월-2014
Publisher
YONSEI UNIV COLL MEDICINE
Keywords
Brugada syndrome; implantable cardioverter-defibrillator; sudden death; syncope; Korea
Citation
YONSEI MEDICAL JOURNAL, v.55, no.1, pp.37 - 45
Indexed
SCIE
SCOPUS
KCI
Journal Title
YONSEI MEDICAL JOURNAL
Volume
55
Number
1
Start Page
37
End Page
45
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/99571
DOI
10.3349/ymj.2014.55.1.37
ISSN
0513-5796
Abstract
Purpose: Our study aims to analyze prognosis after implantable cardioverter-defibrillator (ICD) implantation in Korean patients with Brugada syndrome (BrS). Materials and Methods: This was a retrospective study of BrS patients implanted with an ICD at one of four centers in Korea between January 1998 and April 2012. Sixty-nine patients (68 males, 1 female) were implanted with an ICD based on aborted cardiac arrest (n=38, 55%), history of syncope (n=17, 25%), or induced ventricular tachyarrhythmia on electrophysiologic study in asymptomatic patients (n=14, 20%). A family history of sudden cardiac death and a spontaneous type 1 electrocardiography (ECG) were noted in 13 patients (19%) and 44 patients (64%), respectively. Results: During a mean follow-up of 59 +/- 46 months, 4.6 +/- 5.5 appropriate shocks were delivered in 19 patients (28%). Fourteen patients (20%) experienced 5.2 +/- 8.0 inappropriate shocks caused by supraventricular arrhythmia, lead failure, or abnormal sensing. Six patients were admitted for cardiac causes during follow-up, but no cardiac deaths occurred. An episode of aborted cardiac arrest was a significant predictor of appropriate shock, and the composite of cardiac events in the Cox proportional hazard model [hazard ratio (95% confidence interval) was 11.34 (1.31-97.94) and 4.78 (1.41-16.22), respectively]. However, a spontaneous type 1 ECG was not a predictor of cardiac events. Conclusion: Appropriate shock (28%) and inappropriate shock (20%) were noted during a mean follow-up of 59 +/- 46 months in Korean BrS patients implanted with an ICD. An episode of aborted cardiac arrest was the most powerful predictor of cardiac events.
Files in This Item
There are no files associated with this item.
Appears in
Collections
College of Medicine > Department of Medical Science > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Altmetrics

Total Views & Downloads

BROWSE