Parathyroid hormone, vitamin D levels and urine albumin excretion in older persons: the 2011 Korea National Health and Nutrition Examination Survey (KNHANES)
- Authors
- Kim, Hyun-Woo; Park, Hyunkyoung; Cho, Kyung Hwan; Han, Kyungdo; Ko, Byung-Joon
- Issue Date
- 1월-2014
- Publisher
- WILEY
- Citation
- CLINICAL ENDOCRINOLOGY, v.80, no.1, pp.34 - 40
- Indexed
- SCIE
SCOPUS
- Journal Title
- CLINICAL ENDOCRINOLOGY
- Volume
- 80
- Number
- 1
- Start Page
- 34
- End Page
- 40
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/99624
- DOI
- 10.1111/cen.12246
- ISSN
- 0300-0664
- Abstract
- Objective Persistent elevation of urinary albumin excretion (UAE), even within normal range, is an independent predictor for cardiovascular disease. Accumulating research suggests that low levels of vitamin D and high levels of parathyroid hormone (PTH) also increase cardiovascular disease risk. This study is intended to investigate the relationship between PTH, vitamin D levels and UAE. Methods We examined 2897 adults aged 50 and above, participating in the second year of the fifth Korea National Health and Nutrition Examination Survey (KNHANES V-2). Anthropometric and laboratory measurements were performed. Elevated UAE was defined as spot urinary albumin creatinine ratio equal or above 10. Results The proportion of elevated UAE (21.8%, 23.2%, 23.2%, 31.8%; P for trend = 0.002) rose with increasing quartiles of PTH. The odds ratio for elevated UAE in the highest quartile of PTH was 72% higher than the lowest quartile group. There was no relationship between vitamin D and elevated UAE. Conclusions Elevated PTH levels are associated with elevated UAE in Korean adults aged 50 and above. Additional studies are needed to clarify this relationship.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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