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Phorbasones A and B Sesterterpenoids Isolated from the Marine Sponge Phorbas sp and Induction of Osteoblast Differentiation
- Rho, Jung-Rae;
- Hwang, Buyng Su;
- Joung, Seewon;
- Byun, Mi Ran;
- Hong, Jeong-Ho;
- 외 1명
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Two new sesterterpenoids, phorbasones A (1) and B (2), were isolated from the Korean marine sponge Phorbas sp. Their complete structures were elucidated by spectral data and chemical reactions. Phorbasone A exhibited a positive effect on the calcium deposition activity in C3H10T1/2 cells. The biogenic origin of the core structure is believed to be through a novel rearrangement from the ansellone carbon structure.
키워드
NATURAL-PRODUCTS; STRUCTURE ELUCIDATION; DRUG DISCOVERY; DITERPENES; PHORBOXAZOLE; MACROLIDES
- 제목
- Phorbasones A and B Sesterterpenoids Isolated from the Marine Sponge Phorbas sp and Induction of Osteoblast Differentiation
- 저자
- Rho, Jung-Rae; Hwang, Buyng Su; Joung, Seewon; Byun, Mi Ran; Hong, Jeong-Ho; Lee, Hee-Yoon
- 발행일
- 2011-03-04
- 유형
- Article
- 저널명
- Organic Letters
- 권
- 13
- 호
- 5
- 페이지
- 884 ~ 887
- 언어
- ENG
- 출판사
- AMER CHEMICAL SOC
- 발행국가
- 미국
- 분량
- 4 페이지
- ISSN
- E 1523-7052
P 1523-7060