Incidence of and Risk Factors for Alzheimer's Disease and Mild Cognitive Impairment in Korean Elderly

  • Bae, Jong Bin
  • Kim, You Joung
  • Han, Ji Won
  • Kim, Tae Hui
  • Park, Joon Hyuk
  • ... Jeong, Hyun Ghang
  • 외 6명
Citations

WEB OF SCIENCE

86
Citations

SCOPUS

94

초록

Background/Aims: Knowledge of incidence rates and risk factors is essential for the development of strategies to treat patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI). Methods: A subpopulation of the Nationwide Survey on Dementia Epidemiology (460 Korean subjects aged years from 2 rural and 2 urban districts) was followed up for 3.5 years. The age-specific incidence was estimated and risk factors were identified. Results: The age-standardized incidence of AD and MCI was 7.9 and 28.1 cases per 1,000 person-years, respectively. MCI was associated with a 6-fold increased risk of AD. Depression was a risk factor for AD with MCI. Age, lack of formal education, illiteracy, rural residence, and marital status were associated with the risk of AD. Conclusion: Strategies to control modifiable risk factors should be implemented to decrease the incidence of AD. (C) 20140, Karger AG, Basel.

키워드

Alzheimer's diseaseMild cognitive impairmentEpidemiologyIncidenceRisk factorsKoreaPOPULATION-BASED COHORTDEPRESSIVE SYMPTOMSMARITAL-STATUSDEMENTIAPREVALENCECOMMUNITYSUBTYPESHEALTHASSOCIATIONPROGRESSION
제목
Incidence of and Risk Factors for Alzheimer's Disease and Mild Cognitive Impairment in Korean Elderly
저자
Bae, Jong BinKim, You JoungHan, Ji WonKim, Tae HuiPark, Joon HyukLee, Seok BumLee, Jung JaeJeong, Hyun GhangKim, Jeong LanJhoo, Jin HyeongYoon, Jong ChulKim, Ki Woong
DOI
10.1159/000366555
발행일
2015
유형
Article
저널명
Dementia and Geriatric Cognitive Disorders
39
1-2
페이지
105 ~ 115