Microbial Immobilized Enzyme Biocatalysts for Multipollutant Mitigation: Harnessing Nature's Toolkit for Environmental Sustainability

  • Abdelhamid, Mohamed A. A.; 
  • Khalifa, Hazim O.; 
  • Yoon, Hyo Jik; 
  • Ki, Mi-Ran; 
  • Pack, Seung Pil
Citations

WEB OF SCIENCE

41
Citations

SCOPUS

50

초록

The ever-increasing presence of micropollutants necessitates the development of environmentally friendly bioremediation strategies. Inspired by the remarkable versatility and potent catalytic activities of microbial enzymes, researchers are exploring their application as biocatalysts for innovative environmental cleanup solutions. Microbial enzymes offer remarkable substrate specificity, biodegradability, and the capacity to degrade a wide array of pollutants, positioning them as powerful tools for bioremediation. However, practical applications are often hindered by limitations in enzyme stability and reusability. Enzyme immobilization techniques have emerged as transformative strategies, enhancing enzyme stability and reusability by anchoring them onto inert or activated supports. These improvements lead to more efficient pollutant degradation and cost-effective bioremediation processes. This review delves into the diverse immobilization methods, showcasing their success in degrading various environmental pollutants, including pharmaceuticals, dyes, pesticides, microplastics, and industrial chemicals. By highlighting the transformative potential of microbial immobilized enzyme biocatalysts, this review underscores their significance in achieving a cleaner and more sustainable future through the mitigation of micropollutant contamination. Additionally, future research directions in areas such as enzyme engineering and machine learning hold immense promise for further broadening the capabilities and optimizing the applications of immobilized enzymes in environmental cleanup.

키워드

microbial enzymes; enzyme immobilization; multipollutant contamination; bioremediation; environmental restoration; hydrolases; oxidoreductases; AFFINITY PURIFICATION; TRAMETES-VERSICOLOR; AGARICUS-BISPORUS; BACILLUS-SUBTILIS; FLAVOPROTEIN MONOOXYGENASES; CATALASE-PEROXIDASES; MANGANESE PEROXIDASE; RECOMBINANT LACCASE; SI-TAG; DEGRADATION
제목
Microbial Immobilized Enzyme Biocatalysts for Multipollutant Mitigation: Harnessing Nature's Toolkit for Environmental Sustainability
저자
Abdelhamid, Mohamed A. A.; Khalifa, Hazim O.; Yoon, Hyo Jik; Ki, Mi-Ran; Pack, Seung Pil
DOI
10.3390/ijms25168616
발행일
2024-08
유형
Review
저널명
International Journal of Molecular Sciences
권
25
호
16