An ultra-sensitive colorimetric detection of tetracyclines using the shortest aptamer with highly enhanced affinity

  • Kwon, Young Seop; 
  • Raston, Nurul Hanun Ahmad; 
  • Gu, Man Bock
Citations

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110
Citations

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113

초록

A shortened 8-mer ssDNA aptamer was successfully truncated for four different tetracyclines with high affinity. The ultrasensitive colorimetric detection of oxytetracycline using this shortened aptamer was possible, which was about 500-fold enhanced compared to that obtained using the original 76-mer aptamer.

키워드

UNMODIFIED GOLD NANOPARTICLES; BINDING RIBOSWITCH; DNA APTAMER; RNA APTAMER; THEOPHYLLINE; SEQUENCES; PROSPECTS; DYNAMICS; DESIGN; MOTIF
제목
An ultra-sensitive colorimetric detection of tetracyclines using the shortest aptamer with highly enhanced affinity
저자
Kwon, Young Seop; Raston, Nurul Hanun Ahmad; Gu, Man Bock
DOI
10.1039/c3cc47108j
발행일
2014
유형
Article
저널명
Chemical Communications
권
50
호
1
페이지
40 ~ 42