Recent Advances in the Development of Pharmacologically Active Compounds that Contain a Benzoxazole Scaffold

  • Singh, Sarbjit; 
  • Veeraswamy, Gajulapati; 
  • Bhattarai, Deepak; 
  • Goo, Ja-Il; 
  • Lee, Kyeong; 
  • ... Choi, Yongseok
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초록

In recent years, the emergence of biologically active compounds that contain a heterocyclic ring has gained a great deal of attention among medicinal chemists. Among these, benzoxazole-based compounds are particularly attractive because of their wide range of pharmacological activities. In this focus review, we highlight recent advancements in the development of benzoxazole-based pharmacologically active compounds since the year 2000.

키워드

benzoxazoles; heterocycles; inhibitors; medicinal chemistry; structure-activity relationship; INOSINE 5'-MONOPHOSPHATE DEHYDROGENASE; TOPOISOMERASE-II INHIBITORS; TRANSFER PROTEIN INHIBITORS; SOLUBLE EPOXIDE HYDROLASE; HUMAN NEUTROPHIL ELASTASE; IN-VITRO EVALUATION; BIOLOGICAL EVALUATION; KINASE INHIBITORS; HETEROCYCLIC-COMPOUNDS; ANTIMICROBIAL AGENTS
제목
Recent Advances in the Development of Pharmacologically Active Compounds that Contain a Benzoxazole Scaffold
저자
Singh, Sarbjit; Veeraswamy, Gajulapati; Bhattarai, Deepak; Goo, Ja-Il; Lee, Kyeong; Choi, Yongseok
DOI
10.1002/ajoc.201500235
발행일
2015-12
유형
Article
저널명
Asian Journal of Organic Chemistry
권
4
호
12
페이지
1338 ~ 1361